Am I suffering from rheumatoid arthritis?
A 45-year-old female, 158 cm tall, weighing 45 kg: (1) Menopause occurred in May 2022.
(2) No chronic diseases, no hereditary diseases, no allergies.
(3) Diagnosed with a gastric ulcer via endoscopy in July 2021; chronic gastric acid has caused throat damage (no gastroenterology consultations for 7-8 years).
(4) Has experienced long-term insomnia for 15 years since age 30 (first psychiatric consultation for insomnia in August 2022).
● On July 4, 2022, upon waking, both feet were stiff and painful; walking caused pain in the soles, which eased after some activity, but pain and stiffness in the feet and hands worsened with prolonged rest.
● On July 6, in addition to the feet, there was stiffness and pain in the proximal interphalangeal joints and metacarpophalangeal joints of both hands, making it difficult to make a fist.
After some activity, she could make a fist, but the joints remained stiff throughout the day, sometimes accompanied by pain (pain in the sides of the finger joints varied).
Soaking hands in warm water did not cause stiffness or pain.
● On July 19, at an orthopedic clinic: Blood tests for Latex RA test: [ (-) ] negative.
The doctor prescribed: 50 mg of "Yongsheng" enteric-coated micro-particle capsules for 7 days + "Johnson" muscle relaxant tablets for 7 days, but there was no significant improvement after medication.
● On August 10, referred to rheumatology: Blood tests showed: (1) RF [11.20] (2) ESR [15] (3) Creatinine [0.68] (4) ANA [Negative] (5) CRP [1.45] (6) ALT/GPT [31] (7) AST/GOP [29].
The doctor assessed these blood indices as [normal] - the condition was diagnosed as [recurrent inflammation around the joints].
The doctor prescribed: 5 mg of "Boli" Kangsu Long tablets for 3 days (first day of medication resulted in insomnia) + 200 mg of Xirebao capsules for 7 days, with weekly follow-ups, but there was still no significant improvement.
By the end of August, possibly due to seasonal changes, the pain and stiffness in the hands and feet worsened.
● On August 24, the rheumatologist changed the medication: 500 mg of "Xindong" Salazopyrin enteric-coated tablets for 7 days + 200 mg of Xirebao capsules for 7 days.
After taking the Salazopyrin enteric-coated tablets for one day, throat pain began (continued for three days before stopping), and there have been no follow-ups since.
What condition do my hand and foot joints have? Thank you, doctor.
vivi, 40~49 year old female. Ask Date: 2022/09/06
Dr. Wang Shouji reply Orthopedics
Hello, based on your symptoms, it seems very much like rheumatoid arthritis.
If there is no excessive use of the joints in daily activities, we need to consider whether it is due to intrinsic factors in your body.
The pain in the soles of your feet is more likely to be plantar fasciitis, which typically improves with physical therapy and medication.
Given your symptoms, it appears that the medication has not been very effective, while physical therapy has shown some benefits (helping to alleviate stiffness).
I recommend reducing your activity level and continuing with physical therapy, then returning for a follow-up to assess your joint condition.
Changhua Hospital cares about your health.
Dr.
Wang Shou-ji.
Reply Date: 2022/09/06
More Info
Based on your detailed description of symptoms and medical history, it appears that you are experiencing joint pain and stiffness, particularly in your hands and feet. These symptoms can be indicative of various conditions, including rheumatoid arthritis (RA), but it is essential to consider a comprehensive evaluation to arrive at an accurate diagnosis.
Understanding Your Symptoms
1. Joint Stiffness and Pain: The stiffness you experience upon waking, which improves with movement, is a classic symptom of inflammatory arthritis, including RA. The fact that your symptoms worsen with inactivity and improve with activity is also consistent with inflammatory conditions.
2. Affected Joints: The involvement of proximal interphalangeal joints and metacarpophalangeal joints in your hands, along with the pain in your feet, raises suspicion for RA. RA typically affects joints symmetrically and can lead to morning stiffness lasting more than an hour.
3. Blood Test Results: Your negative rheumatoid factor (RF) and negative anti-nuclear antibody (ANA) tests are significant. While RF is commonly elevated in RA, it can be negative in some patients, especially in the early stages of the disease. The erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels you provided are within normal limits, which may suggest that there is no active systemic inflammation at this time.
4. Previous Medical History: Your history of gastric ulcers and insomnia may not directly relate to your joint symptoms but could affect your overall health and treatment options.
Differential Diagnosis
Given your symptoms and test results, several conditions could be considered:
- Rheumatoid Arthritis: Despite the negative RF, RA cannot be ruled out entirely, especially if your symptoms align with the clinical picture.
- Osteoarthritis: This is less likely given the pattern of stiffness and pain, but it can still be a consideration, particularly if there is a history of joint overuse.
- Psoriatic Arthritis: If you have any skin symptoms or a family history of psoriasis, this could be a possibility.
- Other Inflammatory Conditions: Conditions like ankylosing spondylitis or reactive arthritis could also present with similar symptoms.
Next Steps
1. Further Evaluation: It may be beneficial to undergo additional tests, such as anti-citrullinated protein antibodies (anti-CCP), which can be more specific for RA. Imaging studies like X-rays or ultrasounds of the affected joints may also provide insight into any structural changes.
2. Consultation with a Rheumatologist: Since you have already seen a rheumatologist, it is crucial to maintain follow-up appointments. If your symptoms persist or worsen, further intervention may be necessary.
3. Symptom Management: While medications like NSAIDs (e.g., Celecoxib) can help manage pain and inflammation, it is essential to monitor for side effects, especially given your history of gastric ulcers. Discuss alternative pain management strategies with your healthcare provider.
4. Lifestyle Modifications: Regular low-impact exercise, physical therapy, and heat/cold therapy can help alleviate stiffness and improve joint function.
Conclusion
In summary, while your symptoms may suggest a condition like rheumatoid arthritis, the negative blood tests and the nature of your symptoms indicate that further evaluation is necessary. It is essential to work closely with your healthcare provider to monitor your condition and adjust your treatment plan as needed. If your symptoms continue to progress or if you develop new symptoms, do not hesitate to seek further medical advice.
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