Nipple Discharge: Causes and When to Seek Help - Obstetrics and Gynecology

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Nipple discharge


Hello, Director Cao.
In the past six months, I have occasionally felt a fullness in my left breast, and sometimes a small drop of clear fluid appears on my left nipple, which occasionally stains my clothing (the frequency varies; sometimes it's a few times a week, other times a few times a month).
However, when I squeeze the nipple, no fluid comes out.
Could you please advise what this might indicate and whether I should be concerned? (I have a 0.8 cm nodule in my left breast, which I have been monitoring every six months.) Thank you for your assistance.

Ms. Chen, 50~59 year old female. Ask Date: 2022/09/20

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, it is recommended to have a prolactin hormone test at the hospital.
If the levels are within the normal range, then there is no concern.
Wishing you good health.

Reply Date: 2022/09/20

More Info


Nipple discharge can be a concerning symptom for many individuals, and understanding its potential causes is crucial for determining whether further evaluation is necessary. In your case, the intermittent clear discharge from your left nipple, combined with the sensation of fullness in the breast, warrants careful consideration, especially given your history of a 0.8 cm nodule that is being monitored.

Nipple discharge can arise from various conditions, some benign and others potentially more serious. Common causes of nipple discharge include:
1. Hormonal Changes: Fluctuations in hormone levels, particularly estrogen and progesterone, can lead to changes in breast tissue and result in discharge. This is often seen in women during their menstrual cycle or pregnancy.

2. Duct Ectasia: This condition occurs when a milk duct beneath the nipple dilates, fills with fluid, and thickens. It can lead to discharge, which may be clear, sticky, or even greenish.

3. Intraductal Papilloma: This is a benign tumor that forms in the milk ducts and can cause discharge. It is usually associated with a single duct and may be accompanied by blood-stained discharge.

4. Mastitis or Breast Infection: Infections can lead to inflammation and discharge, often accompanied by pain, redness, and swelling.

5. Breast Cancer: While less common, certain types of breast cancer can present with nipple discharge, particularly if it is bloody or occurs spontaneously without squeezing the nipple.

Given that you have a known breast nodule, it is essential to monitor any changes in your breast health closely. The fact that you are experiencing discharge intermittently and that it is clear is generally less concerning than bloody or persistent discharge. However, the presence of a nodule necessitates regular follow-up and imaging studies, such as ultrasound or mammography, to ensure that there are no changes in the nodule's characteristics.

When to seek help:
- If the discharge becomes persistent or changes in color or consistency (especially if it becomes bloody).

- If you experience any new symptoms, such as breast pain, swelling, or changes in the shape or size of the breast.

- If there are any changes in the nodule, such as increased size or tenderness.

In your case, since you are already undergoing regular monitoring for the breast nodule, it would be prudent to discuss the nipple discharge with your healthcare provider during your next visit. They may recommend further evaluation, such as imaging or possibly a referral to a specialist, to rule out any serious conditions.

In summary, while clear nipple discharge can often be benign, it is essential to remain vigilant, especially with a history of a breast nodule. Regular communication with your healthcare provider and adherence to follow-up appointments will help ensure that any potential issues are addressed promptly.

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