High Creatinine and Uric Acid Levels in Young Adults - Internal Medicine

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Elevated creatinine levels?


Hello doctor, I am currently 18 years old, 170 cm tall, and weigh 47 kg.
During a health check-up, I found that my creatinine level is elevated (1.45) and my uric acid level is also high (9.2).
Additionally, protein was detected in my urine.
Is my kidney function still normal? Do I need further testing?

A-Song, 10~19 year old female. Ask Date: 2022/09/25

Dr. Wu Hongjie reply Internal Medicine


Based on your body type, it appears that you do not have a physique characterized by high muscle mass.
The elevated creatinine levels suggest a need for further evaluation at a clinic.
Wishing you health and safety.

Reply Date: 2022/09/25

More Info


High levels of creatinine and uric acid in young adults can be concerning and warrant further investigation. In your case, at 18 years old with a height of 170 cm and weight of 47 kg, the findings of elevated creatinine (1.45 mg/dL) and uric acid (9.2 mg/dL) alongside the presence of protein in your urine indicate that there may be underlying issues with kidney function or metabolic processes.


Understanding Creatinine and Uric Acid Levels
Creatinine is a waste product generated from muscle metabolism and is typically filtered out of the blood by the kidneys. Normal creatinine levels generally range from about 0.6 to 1.2 mg/dL, depending on muscle mass and other factors. A level of 1.45 mg/dL is slightly elevated, which could suggest that your kidneys are not filtering waste effectively.
Uric Acid is produced from the breakdown of purines, substances found in certain foods and drinks. Normal levels for young adults typically range from 3.5 to 7.2 mg/dL for males. A level of 9.2 mg/dL is significantly high and may indicate a condition known as hyperuricemia, which can lead to gout or kidney stones if not managed properly.


Protein in Urine
The presence of protein in urine (proteinuria) can be a sign of kidney damage or disease. Normally, the kidneys filter blood and prevent significant amounts of protein from entering the urine. If protein is detected, it may indicate that the kidneys are not functioning properly.


Next Steps
Given these findings, it is crucial to take the following steps:
1. Consult a Nephrologist: A kidney specialist can provide a more detailed evaluation of your kidney function. They may recommend additional tests, such as a 24-hour urine collection, imaging studies, or a kidney biopsy, depending on the severity of the findings.

2. Lifestyle Modifications:
- Diet: Reducing the intake of high-purine foods (such as red meats, organ meats, shellfish, and certain fish) can help lower uric acid levels. Increasing hydration by drinking plenty of water can also assist in flushing out uric acid.

- Exercise: Regular physical activity can help maintain a healthy weight and improve overall kidney function.

- Avoid Alcohol: Alcohol can increase uric acid levels and should be limited or avoided.

3. Monitor Symptoms: Keep track of any symptoms such as swelling, pain in joints (especially in the big toe), or changes in urination. Report these to your healthcare provider.

4. Follow-Up Testing: Regular monitoring of your creatinine and uric acid levels, as well as kidney function tests, will be important to assess any changes over time.


Conclusion
In summary, your elevated creatinine and uric acid levels, along with protein in your urine, suggest that further evaluation is necessary to determine the underlying cause and to assess your kidney health. Early intervention can help prevent potential complications, so it is essential to follow up with a healthcare provider promptly. Taking proactive steps in terms of diet, hydration, and lifestyle can also play a significant role in managing your health.

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