Managing Hypertension: Safety and Dosage of Blood Pressure Medications - Cardiology

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Antihypertensive medications


Hello Director: I previously had high blood pressure, and the clinic prescribed "Amlodipine" as an antihypertensive medication, one tablet daily.
My blood pressure is now around 140-130/90.
I would like to ask: 1.
Is it possible to reduce the dosage to half a tablet daily on my own? 2.
Is the composition of this medication safe? 3.
Will long-term use of antihypertensive medication make blood vessels weaker or thinner? Thank you for taking the time to respond! Thank you!

Wang Yun, 50~59 year old female. Ask Date: 2022/10/05

Dr. He Dongjin reply Cardiology


Hello, the blood pressure is approximately 140-130/90, which is still not low.
It is not advisable to reduce the medication.
Is the component of this medication safe? No problem, it will also take care of the heart and reduce the mortality rate from heart failure.
There is no antihypertensive medication that, when taken long-term, will make blood vessels brittle or thin.
Our goal in using medication is to protect the cardiovascular system, not to harm the blood vessels.
Peace and care from Changhua Hospital.

Reply Date: 2022/10/05

More Info


Managing hypertension effectively requires careful consideration of medication, dosage, and the individual patient's health status. In your case, you are currently taking "壓落保" (likely a brand name for a blood pressure medication) and are considering adjusting your dosage. Let’s address your questions one by one.

1. Can I reduce the dosage to half a pill daily?
It is essential to consult your healthcare provider before making any changes to your medication regimen. While it may seem reasonable to reduce the dosage if your blood pressure is within a more acceptable range (like 130-140/90), this decision should be based on a thorough evaluation of your health status. Blood pressure medications are prescribed based on individual needs, and any adjustments should be made under medical supervision to ensure that your blood pressure remains controlled. Self-adjusting your medication can lead to fluctuations in blood pressure, which may increase the risk of cardiovascular events.

2. Is this medication safe?
The safety of any medication, including "壓落保," depends on various factors, including your overall health, any underlying conditions, and potential interactions with other medications you may be taking. Most antihypertensive medications are considered safe when prescribed and monitored by a healthcare professional. However, like all medications, they can have side effects. Common side effects of blood pressure medications may include dizziness, fatigue, or gastrointestinal issues. It is crucial to discuss any concerns about side effects with your doctor, who can provide guidance based on your specific situation.

3. Will long-term use of blood pressure medications weaken or thin my blood vessels?
Long-term use of antihypertensive medications does not inherently weaken or thin blood vessels. In fact, the primary goal of these medications is to manage blood pressure effectively, which helps prevent damage to blood vessels and reduces the risk of complications such as heart attack, stroke, and kidney disease. However, it is important to recognize that uncontrolled hypertension can lead to vascular damage over time. Therefore, maintaining a stable and controlled blood pressure through appropriate medication is vital for vascular health.

In addition to medication, lifestyle modifications play a significant role in managing hypertension. These include maintaining a healthy diet (such as the DASH diet), regular physical activity, weight management, reducing sodium intake, and avoiding excessive alcohol consumption. These changes can enhance the effectiveness of your medication and contribute to overall cardiovascular health.

Lastly, regular follow-up appointments with your healthcare provider are essential for monitoring your blood pressure and adjusting your treatment plan as necessary. If you experience any side effects or have concerns about your medication, do not hesitate to reach out to your doctor for advice. They can provide personalized recommendations based on your health history and current condition.

In summary, while it may be tempting to adjust your medication on your own, it is crucial to involve your healthcare provider in these decisions to ensure safe and effective management of your hypertension.

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