Antibiotic Dosage: Managing Overuse and Side Effects

Antibiotic dosage

Hello, doctor.
I was hospitalized for 4 days due to a peritonsillar abscess.
During my hospital stay, I received antibiotic injections, and I felt much better upon discharge.
The doctor prescribed oral Curran 1000 mg for 7 days, to be taken twice a day, with 2 tablets each time.
On the night of my discharge, I took 2 tablets, and I started to feel nauseous.
Later, I saw the medication leaflet indicating the dosage is 1 tablet twice a day.
I would like to ask if this means I have taken an overdose of the medication?

Cheng, 30~39 year old female. Ask Date: 2022/10/15

Dr. Hong Yuanbin reply Internal Medicine

Hello, whether a medication overdose requires a blood test to check drug levels is indeed a consideration.
However, the nausea you mentioned is a common side effect of this antibiotic and can occur even at normal dosages.
Experiencing nausea does not necessarily indicate an overdose.
It is recommended to drink plenty of water and rest; this discomfort should resolve quickly.
Thank you for your question.

Reply Date: 2022/10/15

More Info

When it comes to antibiotic usage, particularly after a hospital stay for a condition like a peritonsillar abscess, it's crucial to understand both the appropriate dosage and the potential side effects associated with these medications. In your case, you were prescribed Curran (which contains amoxicillin and clavulanate) at a dosage of 1000 mg, to be taken twice daily. However, you took two pills at once on your first night home, which may have led to an overdose, depending on the specific formulation and your individual health status.

Understanding Dosage and Overuse
1. Dosage Guidelines: The standard dosage for Curran is typically one tablet (1000 mg) taken twice a day. Taking two tablets at once would indeed exceed the recommended dosage for that time period. Overdosing on antibiotics can lead to increased side effects and may not provide any additional benefit in treating your condition.

2. Overuse and Resistance: Overuse of antibiotics can lead to antibiotic resistance, a significant public health concern. This occurs when bacteria evolve and become resistant to the effects of medications that once effectively treated infections. It's essential to follow the prescribed dosage strictly to minimize this risk.

3. Side Effects: Common side effects of antibiotics like Curran include nausea, vomiting, diarrhea, and abdominal pain. If you experience severe nausea or vomiting, it may be a direct result of the higher dose you took. If symptoms persist or worsen, it is crucial to contact your healthcare provider.

Managing Side Effects
- Nausea and Vomiting: If you feel nauseous after taking the medication, it may help to take it with food or to split the dose into smaller amounts throughout the day, as long as this is approved by your doctor. Staying hydrated is also essential.

- Monitoring Symptoms: Keep track of any side effects you experience. If you notice severe reactions, such as persistent vomiting, rash, or difficulty breathing, seek medical attention immediately.

Recommendations
1. Consult Your Doctor: Since you experienced nausea after taking the higher dose, it’s advisable to consult your physician about your symptoms and the correct dosage. They may adjust your prescription or provide alternative medications to manage your condition without causing discomfort.

2. Follow Instructions: Always adhere to the instructions provided by your healthcare provider or the medication guide. If you have questions about your medication or its side effects, don’t hesitate to ask your healthcare provider for clarification.

3. Educate Yourself: Understanding your medications, including their purpose, dosage, and potential side effects, empowers you to manage your health better. Always read the patient information leaflet that comes with your medication.

4. Avoid Self-Medication: Never adjust your dosage or switch medications without consulting your healthcare provider. This can lead to ineffective treatment or increased risk of side effects.

Conclusion
In summary, while antibiotics are essential for treating bacterial infections, they must be used judiciously to avoid complications such as overdose and antibiotic resistance. If you have any concerns about your medication or experience adverse effects, reach out to your healthcare provider for guidance. Your health and safety should always come first.

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