Knee Pain: Is It Degenerative Arthritis After Vaccination? - Orthopedics

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Knee joint pain


Hello Doctor, I started receiving vaccinations last year, and initially, I experienced mild pain in my finger joints.
I consulted a rheumatologist, and the blood tests came back normal.
I didn't pay much attention to it and continued with the vaccinations.
After receiving the third dose this year, I began to experience pain in my right ankle joint, which I initially thought was a sprain.
I saw an orthopedic and rehabilitation specialist, and it improved.
However, around July 20, I started having pain in my knee joint.
At first, it was mild, and I could walk, sit, squat, and jog.
I thought it was due to sitting cross-legged, but after changing my position, the pain persisted.
I took medications prescribed by the orthopedic doctor for degenerative arthritis and muscle relaxants, but the effect was not significant, and the pain continued.
However, after sleeping at night, I felt better the next morning.

After receiving the fourth dose at the end of July, the pain worsened that night.
Normally, I would feel better by the next morning after sleeping, but this time the pain persisted from that night until the next morning.
The following day, I experienced vaccine reactions (fever, chills, body aches, and fatigue), and after seeing a doctor and taking medication for a day (three doses, including anti-inflammatory and pain relief), the joint pain subsided.
However, once I stopped the medication, the knee pain returned.
Later, due to vaccine reactions (developing painful lumps under my armpit), I consulted an infectious disease specialist (blood tests were normal) and also for knee pain.
I had an X-ray done (which was normal) and took anti-inflammatory pain relief medication (similar to what I took after the vaccination), which helped.
But the pain returned when I stopped taking the medication.
I then went back to the rheumatologist (blood tests showed normal results but indicated inflammation) and had an ultrasound done, which suggested tendinitis and mild degenerative arthritis.
Since I had not experienced these symptoms or injuries before, I switched to another type of rheumatoid arthritis anti-inflammatory and muscle relaxant.
By mid-August, I noticed that if I took the medication the night before, I would wake up pain-free and normal.
However, after sitting for a long time, when I stood up, the joints would start to hurt and feel stiff (similar to trigger finger, as if the joints were not properly aligned).
Even if I squatted, I would still feel pain the next morning, making it impossible to bend my knee (I couldn't sit or squat).
By the end of September, I was taking anti-inflammatory pain relief medication almost daily, experiencing repeated pain.
Until early October, I confirmed that taking cold medication worked very well (between sitting and standing), allowing me to be very flexible and pain-free.
I am now even simplifying the cold medication (one for cough, one for phlegm, plus one for nasal allergies daily), and it is also effective (currently slightly painful, but I am flexible).

So, I would like to ask, is this a symptom of degenerative arthritis? (In just 2-3 months, my knee feels like it has aged 10-20 years.)

su, 50~59 year old female. Ask Date: 2022/10/17

Dr. Shi Guozheng reply Orthopedics


Joint degeneration is possible, and if medication can provide relief, it is advisable to take some.
Additionally, engaging in rehabilitation can help improve the condition gradually.

Reply Date: 2022/10/17

More Info


Knee pain can be a complex issue, especially when it arises after vaccination or other medical interventions. Based on your description, it seems that you have been experiencing a series of joint-related symptoms following your vaccinations, which have led to concerns about degenerative arthritis or other underlying conditions.

Firstly, it is important to understand that joint pain can have multiple causes, including but not limited to degenerative arthritis, inflammatory conditions, or even post-vaccination reactions. The symptoms you describe—pain in the knee that varies in intensity, relief after rest, and exacerbation after certain activities—are indeed common in degenerative joint conditions, but they can also be influenced by other factors, including recent vaccinations.

Degenerative arthritis, or osteoarthritis, is characterized by the wear and tear of cartilage in the joints, leading to pain, stiffness, and decreased mobility. Your experience of pain that improves with rest and worsens with activity is consistent with this condition. However, the rapid onset of symptoms following vaccination raises the question of whether there is an inflammatory component at play.

Vaccines, including those for COVID-19, can sometimes trigger an immune response that may lead to temporary inflammation in the joints. This phenomenon is generally mild and self-limiting, but in some individuals, it can lead to more pronounced symptoms, especially if there is an underlying predisposition to joint issues. The fact that your symptoms improved with anti-inflammatory medications suggests that inflammation may be a significant factor in your pain.

The involvement of multiple joints, including your fingers and knees, and the fluctuating nature of your symptoms could also suggest a systemic issue, such as an inflammatory arthritis. However, your normal blood tests for autoimmune markers are reassuring and suggest that a systemic autoimmune condition is less likely.

Given the complexity of your symptoms, it would be prudent to consider a few steps moving forward:
1. Continued Monitoring: Keep track of your symptoms, noting any patterns related to activity, rest, and medication use. This information can be valuable for your healthcare provider.

2. Physical Therapy: Engaging in a structured physical therapy program can help strengthen the muscles around your knee, improve flexibility, and potentially reduce pain. A physical therapist can tailor a program to your specific needs and monitor your progress.

3. Consultation with a Specialist: If your symptoms persist or worsen, consider consulting a rheumatologist or an orthopedic specialist. They can provide a more in-depth evaluation and may suggest imaging studies, such as MRI, to assess the condition of your knee joint and surrounding structures.

4. Medication Review: Since you have found relief with certain medications, it may be beneficial to discuss a comprehensive pain management plan with your healthcare provider. This could include a combination of anti-inflammatory medications, physical therapy, and possibly dietary or lifestyle modifications.

5. Lifestyle Modifications: Maintaining a healthy weight, engaging in low-impact exercises (like swimming or cycling), and incorporating anti-inflammatory foods into your diet may also help manage your symptoms.

In conclusion, while your symptoms could be indicative of degenerative arthritis, the timing and nature of your pain suggest that there may be other contributing factors, including post-vaccination inflammation. A thorough evaluation by a healthcare professional, along with appropriate management strategies, can help you navigate this challenging situation and improve your quality of life.

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