Choosing Between Avamys and Nasonex: Which Nasal Spray is Safer? - Otolaryngology

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Choosing a corticosteroid nasal spray?


Hello Dr.
Cheng, I would like to ask you a question: Previously, when I visited an otolaryngologist, the doctor prescribed Avamys nasal spray; later, when I saw a rheumatologist, the doctor prescribed Nasonex nasal spray.
Could you please explain the differences between these two, which one is safer, and which one should I use?

Niming, 20~29 year old female. Ask Date: 2022/10/22

Dr. Zheng Jueyi reply Otolaryngology


Hello, both nasal sprays are very safe; they mainly differ in their steroid components and the way the bottle is pressed.
It is recommended to try one of them first, as individual responses may vary.
You can use one for one to two weeks, and if the results are satisfactory, you can continue using it.
If you find the effect to be insignificant, you may switch to the other option and see how it works for you.

Reply Date: 2022/10/22

More Info


When it comes to choosing between Avamys (fluticasone furoate) and Nasonex (mometasone furoate), both are nasal corticosteroids commonly used to treat allergic rhinitis and other nasal conditions. They work by reducing inflammation in the nasal passages, which helps alleviate symptoms such as nasal congestion, sneezing, and runny nose. However, there are some differences between the two that may influence your choice.

1. Active Ingredients and Mechanism of Action:
Both Avamys and Nasonex contain different active ingredients, but they belong to the same class of medications—corticosteroids. Avamys contains fluticasone furoate, while Nasonex contains mometasone furoate. Both medications work by inhibiting the release of inflammatory mediators, thereby reducing inflammation and associated symptoms in the nasal passages.

2. Dosage and Administration:
Avamys is typically administered as a spray into each nostril once daily, while Nasonex can be used once or twice daily depending on the severity of symptoms. The dosing schedule may impact your choice based on convenience and how often you prefer to use a nasal spray.

3. Onset of Action:
Both medications may take several hours to show initial effects, but full symptom relief may take a few days of consistent use. Some patients may respond better to one medication over the other, so it can be a matter of personal experience.

4. Side Effects:
Both Avamys and Nasonex have similar side effects, which can include nasal irritation, dryness, and occasional nosebleeds. Long-term use of nasal corticosteroids can lead to more serious side effects, such as potential impacts on growth in children, increased intraocular pressure, or systemic effects if used excessively. However, when used as directed, both medications are generally considered safe for most patients.

5. Safety Profile:
In terms of safety, both medications are well-studied and have been shown to be effective with a good safety profile. However, individual responses can vary. If you have specific health concerns or conditions (such as glaucoma, cataracts, or a history of nasal surgery), it is essential to discuss these with your healthcare provider to determine which option is best for you.

6. Personal Preference and Response:
Ultimately, the choice between Avamys and Nasonex may come down to personal preference and how your body responds to each medication. Some patients may find one spray more effective or tolerable than the other. If you have been prescribed both, it may be worth trying each one separately to see which provides better symptom relief with fewer side effects.

Conclusion:
In conclusion, both Avamys and Nasonex are effective nasal sprays for treating allergic rhinitis, and both have a similar safety profile. The best choice for you may depend on your specific symptoms, how you respond to each medication, and any underlying health conditions you may have. It is advisable to consult with your healthcare provider about your symptoms and preferences to make an informed decision. They can provide personalized recommendations based on your medical history and current health status.

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