EMLA Cream for Premature Ejaculation: Effects and Safety - Urology

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I recently visited a doctor due to premature ejaculation, and upon the doctor's recommendation, I purchased EMLA 5% cream from the pharmacy.
However, after researching online, I found that some people say this cream might cause discomfort for women during intercourse.
I would like to know if washing off the cream 30 minutes after application would still retain its anesthetic effect.

Niming, 20~29 year old female. Ask Date: 2022/10/26

Dr. Sun Hongshun reply Urology


Hello: I would recommend using condoms to avoid this issue and also to increase endurance.
If you are unable to adapt to condoms, rinsing off the ointment is another option (it will still have a numbing effect, but EMLA 5% is a short-acting formulation, so the effect will wear off over time).
I hope the above response is helpful to you.

Reply Date: 2022/10/26

More Info


EMLA cream, which contains a combination of lidocaine and prilocaine, is a topical anesthetic commonly used to numb the skin before medical procedures or to relieve pain in certain conditions. In the context of premature ejaculation (PE), EMLA cream can be applied to the penis to reduce sensitivity, potentially helping to prolong the duration of intercourse. However, there are important considerations regarding its use, particularly concerning safety and effects on partners.

When applied, EMLA cream typically requires about 30 minutes to an hour to achieve its full anesthetic effect. This is because the active ingredients need time to penetrate the skin and reach the nerve endings responsible for sensation. If you apply the cream and then wash it off after 30 minutes, some anesthetic effect may still be present, but it will likely be diminished compared to leaving it on for the full recommended duration. The effectiveness can vary based on individual skin absorption rates and the thickness of the application.

Regarding the concern about discomfort for female partners, EMLA cream can indeed cause numbness in the area where it is applied. If the cream is not fully washed off before intercourse, it may lead to reduced sensitivity for the partner, which could be uncomfortable or even unpleasant. This is particularly relevant if the partner is sensitive to topical anesthetics or if the cream is applied excessively. To mitigate this risk, it is advisable to wash the area thoroughly before engaging in sexual activity, especially if the cream has been applied for a longer duration than recommended.

In terms of safety, EMLA cream is generally considered safe when used as directed. However, it is essential to follow the instructions provided by your healthcare provider or the product packaging. Overuse or misuse can lead to side effects such as skin irritation, allergic reactions, or systemic absorption of the anesthetic agents, which could potentially cause more serious complications.

If you are concerned about the effects of EMLA cream on your partner or its effectiveness in treating premature ejaculation, it may be beneficial to discuss these concerns with your healthcare provider. They can provide personalized advice based on your specific situation and may suggest alternative treatments or strategies for managing premature ejaculation that do not involve topical anesthetics.

In summary, while EMLA cream can be effective for managing premature ejaculation, careful consideration should be given to its application and the timing of its removal before sexual activity. Communication with your partner about the use of such products is also crucial to ensure a comfortable and enjoyable experience for both parties.

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