Is Frequent Urination Normal After Taking Doxycycline and Cexime? - Urology

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Urinary issues


Hello doctor, I saw a urologist the day before yesterday.
All tests came back normal, and there was no infection.
The doctor prescribed me DOXYCYCLINE, CEFIXIME, and UROPRIN.
After taking them, I have been drinking a lot of water, more than usual, and I keep needing to urinate.
Is this normal?

Kai, 20~29 year old female. Ask Date: 2022/11/01

Dr. Du Shixi reply Urology


Hello: Drink 2000-3000 cc of water.
A light yellow urine color is acceptable, and a urine output of more than 200 cc at a time is considered normal.
If you still feel unwell, please return for a follow-up consultation.
Wishing you good health.

Reply Date: 2022/11/01

More Info


Frequent urination after taking medications like Doxycycline and Cexime can be concerning, especially if it is accompanied by increased thirst or changes in urine color. However, it is essential to understand that the medications you are taking may have varying effects on your urinary system and hydration status.

Doxycycline is a tetracycline antibiotic commonly used to treat bacterial infections, including those of the urinary tract. While it is generally well-tolerated, some individuals may experience side effects such as gastrointestinal discomfort, which can lead to increased fluid intake as a compensatory measure. If you are drinking more water than usual, this could naturally lead to more frequent urination.
Cexime, on the other hand, is a cephalosporin antibiotic that is also used to treat bacterial infections. Similar to Doxycycline, it does not typically cause increased urination directly. However, if you are experiencing any side effects from these medications, such as nausea or diarrhea, you might be prompted to drink more fluids, which can also contribute to increased urination.

Uroprin, which is often used to relieve urinary tract discomfort, may also influence your urinary habits. It is designed to alleviate symptoms such as burning or urgency, but it does not typically cause increased urination. However, if you are experiencing any irritation or discomfort in your urinary tract, you may feel the need to urinate more frequently.

In your case, since you mentioned that you have been drinking significantly more water than usual, it is likely that the increased frequency of urination is a result of your higher fluid intake. The normal range for urine output is about 800 to 2000 milliliters per day, depending on fluid intake, and urinating more frequently can be a normal response to increased hydration.

However, if you notice any additional symptoms such as pain during urination, blood in the urine, or if the frequency of urination becomes bothersome, it would be advisable to follow up with your healthcare provider. They may want to conduct further evaluations to rule out any underlying issues, even if initial tests showed no infection.

In summary, while increased urination can be a side effect of medications or a response to increased fluid intake, it is essential to monitor your symptoms closely. If you continue to experience discomfort or have concerns about your urinary habits, do not hesitate to reach out to your healthcare provider for further guidance. Staying hydrated is important, but balance is key, and your provider can help ensure that your treatment plan is effective and appropriate for your needs.

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