Safety of Medications During Breastfeeding: A Pediatric Perspective - Pediatrics

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Medication Issues During Breastfeeding


Hello Doctor, I currently have a cold with a sore throat, phlegm, and a severe cough.
I would like to ask about the safety of the following medications for my 11-month-old baby while I am breastfeeding.
Will these medications affect my baby? 1.
Panadol 500mg (paracetamol) 2.
Fynadine f.c 60mg 3.
Cetylpyridinium chloride 4.
Frikemin, active ingredient: mequitazine.
Thank you for taking the time to reply.
Wishing you all the best.

33, 30~39 year old female. Ask Date: 2022/11/06

Dr. Xiao Kaiwen reply Pediatrics


Generally speaking, except for immunosuppressive drugs, cytotoxic medications, and radioactive drugs, most medications only appear in trace amounts in breast milk and have minimal impact on the baby.
Therefore, there is usually no need to stop breastfeeding.
As a principle, it is advisable to space out breastfeeding and medication administration by breastfeeding first or expressing milk for later use, and then taking the medication immediately afterward.
By the time of the next breastfeeding, the concentration of the medication in the milk will be relatively low, reducing its potential effects on the infant.

Reply Date: 2022/11/06

More Info


When considering the safety of medications during breastfeeding, it is crucial to evaluate each medication's potential effects on both the mother and the infant. Here, I will address the specific medications you mentioned and their implications for breastfeeding.

1. Panadol (Paracetamol): Paracetamol is widely regarded as safe for use during breastfeeding. It is a common analgesic and antipyretic that does not significantly transfer into breast milk. Studies have shown that the levels of paracetamol in breast milk are low and are unlikely to cause any adverse effects in a breastfeeding infant. Therefore, you can use Panadol to manage pain or fever while breastfeeding without significant concern.

2. Fynadine (Fexofenadine): Fexofenadine is an antihistamine used to treat allergic symptoms. It is considered safe during breastfeeding as well. Limited studies indicate that fexofenadine is excreted in breast milk in very small amounts, and it is unlikely to affect a nursing infant. However, as with any medication, it is advisable to monitor your baby for any unusual symptoms, especially if you are taking it for an extended period.

3. Cetylpyridinium Chloride: This compound is often found in throat lozenges and mouthwashes as an antiseptic. While there is limited data specifically regarding its safety during breastfeeding, it is generally considered safe for short-term use. The amount that could potentially transfer into breast milk is minimal, and it is unlikely to pose a risk to your infant. However, if you notice any adverse reactions in your baby, you should consult your healthcare provider.

4. Frikemin (Mequitazine): Mequitazine is another antihistamine, primarily used for allergic conditions. There is limited information available regarding its safety during breastfeeding. While it is not classified as contraindicated, caution is advised. The potential for drowsiness in both the mother and infant should be considered. If you choose to use this medication, it is best to do so under the guidance of your healthcare provider, who can help weigh the benefits against any potential risks.

In summary, while Panadol and fexofenadine are generally considered safe during breastfeeding, caution should be exercised with cetylpyridinium chloride and mequitazine due to limited data. Always consult your healthcare provider before starting any new medication while breastfeeding, as they can provide personalized advice based on your specific health needs and circumstances.

Additionally, it is essential to maintain open communication with your healthcare provider about any medications you are taking, especially if you notice any changes in your infant's behavior or health. Regular check-ups and monitoring can help ensure both your safety and that of your baby while managing your health conditions.

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