Impact of Laparoscopic Surgery and Anesthesia on Early Pregnancy - Obstetrics and Gynecology

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Pregnancy discovered after laparoscopic surgery?


I had a laparoscopic cholecystectomy on October 13, and on November 9, I found out that I am 7 weeks pregnant.
Will the abdominal and chest X-rays taken before the surgery, as well as the surgical procedure and anesthesia medications, have any effects on the fetus? Thank you.

tingtinglin, 30~39 year old female. Ask Date: 2022/11/10

Dr. Huang Yuande reply Obstetrics and Gynecology


Basically, there will be some impact, but a single X-ray should not have a significant effect.
The impact caused by medication is approximately between 0.5% to 1%.
Therefore, it is still necessary to undergo prenatal check-ups and consultations.
What I emphasize is the concept of "probability" and the level of risk you can tolerate; that is the real consideration.

Reply Date: 2022/11/10

More Info


The impact of laparoscopic surgery and anesthesia on early pregnancy is a topic of significant concern for many expectant mothers. In your case, you underwent laparoscopic cholecystectomy (gallbladder removal) on October 13, and subsequently discovered you were pregnant on November 9, at approximately seven weeks gestation. It is understandable to be anxious about the potential effects of the surgery and the anesthesia used during the procedure on your developing fetus.

Firstly, it is important to note that laparoscopic surgery is generally considered a minimally invasive procedure. This means that it typically involves smaller incisions and less trauma to the body compared to open surgery. The risks associated with laparoscopic surgery during early pregnancy are generally lower, especially when compared to more invasive surgical techniques. However, any surgical procedure carries some inherent risks, including the potential for complications that could indirectly affect the pregnancy.

Regarding the anesthesia used during your surgery, it is crucial to understand that the medications administered during laparoscopic surgery are typically classified based on their safety for use in pregnant individuals. The anesthetic agents commonly used, such as fentanyl and propofol, have varying degrees of safety profiles. Fentanyl, for example, is classified as a Category C drug by the FDA, which means that while animal studies have shown adverse effects, there are no well-controlled studies in humans. This classification indicates that the drug should only be used if the potential benefits justify the potential risks to the fetus.

In your case, since the surgery occurred before you were aware of your pregnancy, the immediate concern is whether the exposure to anesthesia and any potential effects from the surgery could have impacted the embryo. During the early stages of pregnancy, particularly within the first few weeks post-conception, the embryo is undergoing critical stages of development. However, it is also during this time that the embryo is less susceptible to teratogenic effects (causing malformations) from external factors, as it is still in the process of cell division and has not yet formed major organs.

As for the X-rays taken prior to the surgery, it is important to note that while radiation exposure can pose risks during pregnancy, the levels of radiation from standard abdominal and chest X-rays are generally considered low. The risk of harm to the fetus from such imaging is minimal, especially if the exposure is limited and the procedure was necessary for your health.

In summary, while there are always risks associated with surgery and anesthesia, the likelihood of significant adverse effects on your pregnancy from the laparoscopic cholecystectomy and the anesthesia used is low, especially since the procedure was performed before you were aware of your pregnancy. It is always best to discuss any concerns with your obstetrician or healthcare provider, who can provide personalized advice based on your medical history and the specifics of your case. They can also monitor your pregnancy closely to ensure that both you and your baby remain healthy throughout the gestation period.

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