The Risks and Benefits of Using Purple Root in Herbal Remedies

The effects of Lithospermum (Purple Root) and its potential side effects?

Hello Dr.
Ding, I am a housewife who enjoys doing some crafts at home.
Recently, handmade soap has become quite popular, and I have purchased some books to follow recipes.
One of the soaps I made includes adding purple root (Lithospermum) for natural coloring.
However, I have read in some newspapers that purple root is not a safe herb.
I would like to share an article titled "Purple Root Causes Inflammation and Is Harmful to the Liver" from the China Times, dated March 4, 2000, by the Associated Press from Chapel Hill.

It is generally believed that herbal remedies are safe, but scientists at an international conference at the University of North Carolina pointed out that at least one herb is known to cause severe liver damage, suggesting that more in-depth research on herbs is needed.
The herb discussed at the conference was purple root, which is said to have anti-inflammatory, analgesic, and antibacterial effects, making it a common herbal remedy in the United States.

Dr.
Stick from the Heidelberg University Medical Center stated that based on limited clinical studies, the efficacy of purple root has not been proven, and it may destroy small blood vessels in the liver, leading to abdominal pain, liver enlargement, and liver failure.
He mentioned that both Germany and Canada have restricted the use of purple root, making it difficult to understand why there are no restrictions in the United States.

The conference also discussed other herbal remedies, including St.
John's Wort for depression, garlic for cholesterol control and cancer prevention, ginkgo biloba for treating dementia, feverfew for migraines, and sea buckthorn for boosting the immune system and preventing colds.

I would like to ask the doctor if there are any side effects associated with purple root?

Jiātíng zhǔfù, 30~39 year old female. Ask Date: 2003/10/24

Dr. Ding Hanxiang reply Traditional Chinese Medicine

Hello! In Traditional Chinese Medicine, Lithospermum (Zi Cao) has the effects of cooling the blood, promoting blood circulation, and clearing heat.
It is commonly used for measles or skin rashes with good efficacy.
The typical dosage is 1-3 grams per day, which is not large.
Clinically, no significant side effects have been observed.
However, in foreign countries, herbal medicines are often treated as dietary supplements and do not require a physician's guidance for use.
This may lead to the public being unable to assess the indications and dosages for Lithospermum, resulting in the aforementioned situations.
It is important to emphasize that Chinese herbal medicine is still a form of medication and should only be used after being prescribed by a physician.
Sincerely, Dr.
Ding Han-Hsiang, Department of Traditional Chinese Medicine, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2003/10/24

More Info

The use of herbal remedies, including Purple Root (also known as Lithospermum erythrorhizon), has gained popularity for its purported anti-inflammatory and antimicrobial properties. However, as you have rightly pointed out, there are significant concerns regarding its safety, particularly concerning liver health.

Benefits of Purple Root
Purple Root has been traditionally used in various cultures for its potential therapeutic effects. It is often touted for its anti-inflammatory properties, which can be beneficial in treating conditions such as skin irritations, wounds, and even certain inflammatory diseases. Some proponents claim that it can help with pain relief and has antibacterial effects, making it a popular choice in herbal medicine.

Risks and Concerns
Despite these potential benefits, the safety profile of Purple Root is questionable. Research, including studies presented at international conferences, has indicated that Purple Root may pose serious risks to liver health. Specifically, it has been associated with hepatotoxicity, which refers to liver damage caused by chemical substances. The concerns include:
1. Liver Damage: Studies have suggested that Purple Root can destroy small blood vessels in the liver, leading to conditions such as abdominal pain, liver enlargement, and even liver failure. This is particularly alarming as liver health is crucial for overall bodily function, including detoxification and metabolism.

2. Lack of Regulation: In many countries, including the United States, herbal remedies like Purple Root are not as strictly regulated as pharmaceuticals. This lack of oversight can lead to variability in product quality, potency, and safety, increasing the risk of adverse effects.

3. Limited Clinical Evidence: While there are anecdotal reports of the benefits of Purple Root, clinical studies validating its efficacy and safety are limited. The absence of robust scientific evidence raises concerns about its use, especially when safer alternatives are available.

4. Potential for Drug Interactions: Herbal remedies can interact with prescription medications, potentially leading to harmful effects. For individuals taking medications that affect liver function or those with pre-existing liver conditions, the use of Purple Root could exacerbate health issues.

Recommendations
Given the potential risks associated with Purple Root, it is advisable to approach its use with caution. Here are some recommendations:
- Consult a Healthcare Professional: Before incorporating any herbal remedy into your routine, especially one with known risks, consult with a healthcare provider. They can provide personalized advice based on your health history and current medications.

- Consider Alternatives: If you are looking for natural dyes for your handmade soaps, consider safer alternatives that do not carry the same risks as Purple Root. There are many natural colorants derived from fruits, vegetables, and other plants that are known to be safe.

- Stay Informed: Keep yourself updated on the latest research regarding herbal remedies. Understanding the benefits and risks associated with any substance is crucial for making informed decisions about your health.

- Monitor for Side Effects: If you choose to use Purple Root or any herbal remedy, be vigilant for any signs of adverse effects, particularly those related to liver function, such as jaundice (yellowing of the skin or eyes), dark urine, or abdominal pain. If you experience any of these symptoms, seek medical attention immediately.

In conclusion, while Purple Root may have some traditional uses in herbal medicine, the potential risks, particularly concerning liver health, cannot be overlooked. It is essential to weigh the benefits against the risks and to seek professional guidance before using such remedies.

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