Post-COVID Weakness: Neurological Symptoms and Recovery - Neurology

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Weakness in the limbs after diagnosis?


Dear Dr.
Tsai,
During my diagnosis on September 2, I experienced weakness in my limbs, which gradually evolved into weakness only when exerting force.
I can normally pick up objects, but I have noticed that when performing fine motor tasks, my hands tremble.
For example, when buttoning, reaching into my pocket to find something, or using my fingers to pick my nose, I exhibit weakness and trembling.
Previously, I underwent a carotid ultrasound at Taipei Medical University Hospital, which showed normal results.

I would like to ask, Dr.
Tsai, can the COVID-19 virus lead to autonomic nervous system dysfunction, resulting in muscle weakness? Have you encountered similar cases like mine after diagnosis? What additional tests would you recommend, or could this be a typical symptom of long COVID? Will the autonomic nervous system self-repair in a few months? It has been over two months, and I have been experiencing postural tachycardia (with no abnormalities found in the cardiac series tests at Taipei Medical University), which makes me very anxious.
I can only lie down quietly every day, and I have sought help at Taipei Medical University and Veterans General Hospital, both of which reported normal results.
I sincerely ask for your valuable advice and insights.
I am very grateful to you.

Miss Jian, 40~49 year old female. Ask Date: 2022/11/19

Dr. Cai Zongzhang reply Neurology


Hello, Miss Jian: The symptoms mentioned above may be indicative of a peripheral neuropathy.
It is recommended to consult a neurologist for further evaluation.

Reply Date: 2022/11/19

More Info


Post-COVID symptoms, particularly neurological manifestations, have become a significant concern for many individuals recovering from COVID-19. Your experience of weakness, especially during fine motor tasks, along with tremors, is indeed a symptom that has been reported by others who have experienced COVID-19. This phenomenon is often referred to as "long COVID" or "post-acute sequelae of SARS-CoV-2 infection (PASC)," which encompasses a range of symptoms that persist beyond the acute phase of the infection.

The symptoms you describe, such as weakness and tremors during fine motor activities, could be attributed to several factors related to the aftermath of COVID-19. One possibility is the impact of the virus on the nervous system, which can lead to dysregulation of the autonomic nervous system. This dysregulation can manifest as muscle weakness, tremors, and other neurological symptoms. The autonomic nervous system controls involuntary bodily functions, and when it is disrupted, it can lead to a variety of symptoms, including those affecting muscle control and coordination.

Research has shown that COVID-19 can affect the central nervous system, leading to symptoms such as cognitive impairment, fatigue, and motor dysfunction. The inflammation caused by the virus may also contribute to these neurological symptoms. In your case, the tremors and weakness during specific tasks could be a result of this neurological involvement.

Regarding your concerns about recovery, many individuals report gradual improvement over time, but the timeline can vary widely. Some people may experience lingering symptoms for months, while others may see a resolution of symptoms within a few weeks. The autonomic nervous system can take time to recalibrate, and while some individuals may experience self-resolution of symptoms, others may require targeted interventions.

In terms of further evaluation, it may be beneficial to consult with a neurologist who specializes in post-viral syndromes. They may recommend additional tests, such as nerve conduction studies or electromyography (EMG), to assess the function of your nerves and muscles. These tests can help determine if there is any underlying nerve damage or dysfunction contributing to your symptoms.

Additionally, physical therapy may be a valuable component of your recovery. A physical therapist can work with you to develop a tailored exercise program that focuses on improving strength, coordination, and overall function. Occupational therapy may also be beneficial, particularly for fine motor skills and daily activities.

It's important to maintain open communication with your healthcare providers about your symptoms and concerns. If you notice any new or worsening symptoms, or if your current symptoms are significantly impacting your quality of life, do not hesitate to seek further medical advice.

In summary, your symptoms of weakness and tremors following COVID-19 are not uncommon and may be related to autonomic nervous system dysregulation. While many individuals experience gradual improvement, it is essential to seek appropriate evaluations and interventions to support your recovery. Engaging with specialists and considering physical and occupational therapy can be beneficial as you navigate this challenging phase of recovery. Remember to prioritize self-care and reach out for support when needed.

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