Is It Safe to Get Novavax COVID Vaccine Before Embryo Transfer? - Obstetrics and Gynecology

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Fertility preparation issues


Hello Doctor: I have completed the egg retrieval process and am now preparing for embryo transfer.
Is it currently appropriate for me to receive the Novavax COVID-19 vaccine? Thank you.

Miss Chen, 30~39 year old female. Ask Date: 2022/11/21

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, if you have already received three doses of the vaccine, there is no rush to get another one.
If you choose to get vaccinated, it is advisable to wait until your pregnancy is stable.
Wishing you good health.

Reply Date: 2022/11/21

More Info


When considering the safety of receiving the Novavax COVID-19 vaccine before an embryo transfer, there are several factors to take into account. Firstly, it is essential to understand that the timing of vaccinations in relation to fertility treatments is a topic of ongoing research and discussion among healthcare professionals.

From the information provided, it appears that you have already completed the egg retrieval process and are preparing for embryo transfer. In general, the recommendation is to prioritize your health and the health of your future pregnancy. Vaccination against COVID-19 is crucial, especially given the ongoing pandemic and the potential risks associated with COVID-19 infection during pregnancy.

The Novavax vaccine, like other COVID-19 vaccines, has been shown to be effective in preventing severe illness from the virus. While there is limited specific data on the Novavax vaccine's effects on fertility or embryo transfer, the available evidence suggests that COVID-19 vaccines do not negatively impact fertility or pregnancy outcomes. In fact, vaccination may provide additional protection against severe disease, which is particularly important for individuals undergoing fertility treatments.

If you are considering getting vaccinated with Novavax before your embryo transfer, it is advisable to consult with your fertility specialist or healthcare provider. They can provide personalized guidance based on your medical history, the specifics of your fertility treatment, and any potential risks associated with vaccination at this stage.

In general, if you have already received three doses of a COVID-19 vaccine, there may not be an immediate need to get another dose before the embryo transfer. However, if you have not been vaccinated or are due for a booster, it may be beneficial to get vaccinated after discussing it with your healthcare provider. They may recommend waiting until after the embryo transfer to minimize any potential stress or side effects from the vaccine during this critical time.

Furthermore, it is essential to monitor your health closely after vaccination. Common side effects of COVID-19 vaccines can include mild to moderate symptoms such as fatigue, headache, muscle pain, or fever, which typically resolve within a few days. If you experience any severe or prolonged symptoms, it is crucial to seek medical attention.

In summary, while there is no definitive contraindication to receiving the Novavax vaccine before an embryo transfer, it is essential to have an open discussion with your healthcare provider to weigh the benefits and risks based on your individual circumstances. Vaccination is an important step in protecting your health and the health of your future pregnancy, and your healthcare team can help you make the best decision for your situation.

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