Autonomic nervous system dysfunction
Dr.
Chen: I would like to ask you again about my autonomic nervous system disorder.
The medications prescribed by my doctor are: (1) Foan (OXAZEAM) 10 mg, (2) Diazepam 2 mg, (3) Sulipride 50 mg, which I currently take once daily.
Due to feeling very fatigued upon waking up a month ago (on September 25), I reduced the medication to: (1) Foan (OXAZEAM) 10 mg, (2) Diazepam 1 mg (cutting the tablet in half), (3) Sulipride 25 mg (cutting the tablet in half).
I would like to ask the doctor: (1) Is it necessary to regularly monitor liver function and complete blood count while taking Foan? How often should this be done? (2) I have been experiencing gastrointestinal discomfort (a sensation of food lingering in my stomach and persistent bloating).
Are there any medications among those I am taking that could affect gastrointestinal motility, or could this be due to my autonomic nervous system disorder? (3) Considering the side effects and therapeutic effects of the aforementioned medications, is it better to take a smaller dose of medication long-term, or is it preferable to take multiple doses throughout the day but for shorter durations? (4) I have been experiencing insomnia recently and am unsure if I have developed a dependency on the medication (since starting on June 11).
Is it okay to take melatonin (2 mg at a time)? (5) In the late afternoon approaching evening, my skin temperature increases (but I do not have a fever).
Could this be caused by my autonomic nervous system disorder? (6) Is it appropriate to change doctors and medications midway? (My current doctor was referred by a friend and is qualified in both Western and Traditional Chinese medicine.
In addition to the medications mentioned above, I am also taking Chinese herbal medicine.)
Johnson Jin, 30~39 year old female. Ask Date: 2003/10/28
Dr. Chen Wenke reply Psychiatry
1.
In principle, this type of medication does not significantly impact liver function or blood parameters, so regular monitoring is not necessary.
2.
The medication you are currently taking does affect certain gastrointestinal functions, but it should have a positive effect.
3.
Based on my understanding of your situation, this aspect may require a longer duration of treatment to achieve better results.
4.
Regarding the efficacy and differences of melatonin, there is indeed a significant variation; you can give it a try, but if you do not notice any substantial benefits, it is not necessary to continue using it.
5.
Yes.
6.
From the medications you are currently using, it appears that your physician is quite competent and does not prescribe an excessive amount of medication.
Reply Date: 2003/10/28
More Info
Understanding autonomic nervous system (ANS) disorders, particularly in the context of anxiety and related symptoms, is crucial for effective management and treatment. Your current medication regimen, which includes Foan (Oxazepam), Diazepam, and Sulipride, indicates that you are being treated for anxiety and possibly other related conditions. Let’s address your questions systematically.
1. Regular Monitoring of Liver Function and Blood Counts:
Medications like Oxazepam and Diazepam can have implications for liver function, especially with long-term use. It is generally recommended to monitor liver function tests (LFTs) periodically, particularly if you are on these medications for an extended period. A common practice is to check LFTs every 6 to 12 months, but your healthcare provider may adjust this based on your individual health status and any symptoms you may experience.
2. Gastrointestinal Issues:
The sensation of food lingering in your stomach and feelings of bloating could be influenced by several factors. Both Sulipride and the benzodiazepines (Oxazepam and Diazepam) can affect gastrointestinal motility. Benzodiazepines can lead to relaxation of the gastrointestinal tract, potentially causing delayed gastric emptying. Additionally, autonomic nervous system dysfunction can also contribute to gastrointestinal symptoms. It would be prudent to discuss these symptoms with your physician, as they may need to evaluate your medication regimen or consider additional treatments for gastrointestinal health.
3. Medication Dosing Strategy:
The choice between taking a smaller amount of medication less frequently versus a higher dose more frequently depends on the specific medication, its pharmacokinetics, and your individual response. Some patients may benefit from a steady state of medication in their system, while others may find that splitting doses helps manage symptoms better. It’s essential to have an open discussion with your healthcare provider about your experiences with the current dosing schedule and any side effects you may be experiencing.
4. Insomnia and Potential Dependence:
Benzodiazepines can lead to dependence, especially with prolonged use. If you have been taking these medications since June, it’s possible that your body has developed some level of tolerance or dependence. Melatonin can be a helpful supplement for sleep, but it’s best to consult your doctor before adding it to your regimen, especially regarding the appropriate dosage and timing.
5. Skin Temperature Changes:
Fluctuations in skin temperature, particularly in the afternoon or evening, can indeed be related to autonomic nervous system dysfunction. The ANS regulates body temperature, and dysregulation can lead to sensations of warmth or changes in skin temperature without actual fever. Monitoring these symptoms and discussing them with your healthcare provider is advisable, as they can help determine if further evaluation is needed.
6. Changing Physicians and Medications:
If you feel that your current treatment is not effective or if you have concerns about your physician’s approach, it is entirely appropriate to seek a second opinion or change healthcare providers. It’s important to have a healthcare provider with whom you feel comfortable discussing your symptoms and treatment options. If you decide to switch, ensure that your new provider is fully aware of your medical history and current medications to facilitate a smooth transition.
In summary, managing autonomic nervous system disorders, particularly when intertwined with anxiety and medication, requires a comprehensive approach. Regular monitoring, open communication with your healthcare provider, and a willingness to adjust treatment plans as necessary are key components of effective management. Always prioritize your health and well-being, and don't hesitate to advocate for yourself in your treatment journey.
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