Positron Emission Tomography (PET)
Hello, Director.
Please help me review my mother's PET scan report; I don't understand it.
Thank you.
PET Scan Report:
Indication: The 49-year-old woman is diagnosed with right middle lung cancer, stage IA1 (pT1aNx), status post wedge resection.
An FDG-PET/CT study was arranged for staging.
Procedure: Fasting for more than 4 hours; blood sugar: 120 mg/dl.
Radiotracer: FDG 305 MBq (IV) followed by rest for 1 hour.
Scan protocol: low dose CT (C-) and PET (3D TOF) from head to toe.
Content:
1.
There was mildly increased FDG uptake in the right middle lung (SUVmax: 1.1) and right chest wall (SUVmax: ~1.7), likely due to post-operative changes.
2.
A focal area of mildly increased FDG uptake was noted in the right pulmonary hilar region (SUVmax: 2.5), likely indicating reactive lymph nodes.
3.
A focal area of increased FDG uptake was observed in the right cervical para-tracheal region (or right thyroid gland) (SUVmax: 3.1).
4.
There was diffuse mildly increased FDG uptake in the bone marrow of the axial skeleton and bilateral humeral and femoral shafts, likely due to increased bone marrow activity secondary to chronic anemia.
5.
Physiological FDG uptake and accumulation were observed in the brain, tonsils, salivary glands, heart, liver, spleen, gastrointestinal tracts, and genitourinary tracts.
6.
No definite abnormal FDG uptake was demonstrated elsewhere.
Impression:
1.
Findings are compatible with right middle lung cancer, status post operation.
2.
An FDG-avid lesion in the right cervical para-tracheal region (or right thyroid gland), possibly a thyroid nodule or other pathology.
Clinical correlation and thyroid ultrasound are suggested.
Jia, 40~49 year old female. Ask Date: 2022/12/07
Dr. Chen Sirong reply Oncology
Home / 48 years old / Female 0: It should be based on the explanation from her attending physician.
1.
There were mildly increased FDG uptake in the right middle lung (SUVmax: 1.1) and right chest wall (SUVmax: ~1.7), probably post-operative changes.
There is a post-operative reaction in the right middle lobe of the lung.
2.
There was a focal area of mildly increased FDG uptake in the right pulmonary hilar region (SUVmax: 2.5), probably reactive lymph nodes.
The right hilar lymph nodes show changes consistent with benign inflammatory response.
3.
There was a focal area of increased FDG uptake in the right cervical para-tracheal region (or right thyroid gland) (SUVmax: 3.1).
The uptake point in the right cervical area is adjacent to the trachea; please clinically evaluate or confirm with a thyroid ultrasound to check for any issues.
Other findings are unremarkable; the real concern lies in point 3.
Please consult the original attending physician on how to proceed.
Wishing you peace and health, Dr.
Chen Sih-Rong.
Reply Date: 2022/12/07
More Info
Understanding PET Scan Results for Lung Cancer: A Guide for Patients
When it comes to interpreting PET (Positron Emission Tomography) scan results, especially in the context of lung cancer, it can be quite challenging for patients and their families. The PET scan is a powerful imaging tool that helps in assessing the metabolic activity of tissues, which can provide critical information about cancer staging, treatment response, and potential recurrence. In your mother's case, the PET scan results indicate several key findings that we can break down for better understanding.
Key Findings from the PET Scan
1. Increased FDG Uptake: The report mentions mildly increased FDG (Fluorodeoxyglucose) uptake in the right middle lung and right chest wall. The SUVmax (Standardized Uptake Value maximum) of 1.1 in the lung and approximately 1.7 in the chest wall suggests that these areas are showing some metabolic activity. However, the values are relatively low, which often indicates post-operative changes rather than active cancer.
2. Hilar Region Activity: There is a focal area of mildly increased FDG uptake in the right pulmonary hilar region with an SUVmax of 2.5. This could suggest reactive lymph nodes, which may be responding to the surgical intervention or inflammation rather than malignancy.
3. Cervical Region Uptake: The report notes a focal area of increased FDG uptake in the right cervical para-tracheal region (or right thyroid gland) with an SUVmax of 3.1. This finding is significant and warrants further investigation, as it could represent a thyroid nodule or another condition that may require clinical correlation and possibly a thyroid ultrasound.
4. Bone Marrow Activity: The diffuse mildly increased FDG uptake in the bone marrow of the axial skeleton and limbs is likely due to increased bone marrow activity, possibly secondary to chronic anemia. This is a common finding and may not be directly related to cancer.
5. Physiological Uptake: The report also notes normal physiological uptake in various organs, including the brain, liver, and gastrointestinal tract, which is expected and indicates that these areas are functioning normally.
6. No Other Abnormalities: Importantly, the report states that no definite abnormal FDG uptake can be demonstrated elsewhere, which is a reassuring sign.
Interpretation and Next Steps
The overall impression from the PET scan is compatible with your mother's history of right middle lung cancer, particularly following her wedge resection. The findings suggest that while there are areas of increased uptake, they are likely related to post-operative changes or benign processes rather than active disease.
Given the presence of the FDG-avid lesion in the cervical region, it is advisable to follow up with your healthcare provider for further evaluation. This may include a thyroid ultrasound or additional imaging studies to clarify the nature of the lesion.
Clinical Correlation
It is essential to correlate these imaging findings with clinical symptoms and laboratory results. Your mother's oncologist will consider her entire clinical picture, including her surgical history, any symptoms she may be experiencing, and other diagnostic tests, to determine the best course of action.
Conclusion
In summary, while PET scans can provide valuable insights into cancer staging and treatment response, they must be interpreted in the context of the patient's overall clinical picture. The findings in your mother's report suggest that there are no signs of active disease in the lung, but further investigation of the cervical lesion is warranted. Always discuss the results with your healthcare provider, who can provide personalized guidance and recommendations based on the latest medical evidence and your mother's specific situation.
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