Contraindications for Using Circulating Medications - Pharmacology

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Contraindications for the use of Xunli Ning (a traditional Chinese medicine)?


Hello, I would like to ask about medication usage.
I am currently recovering from spinal surgery and my doctor has prescribed the non-steroidal anti-inflammatory drug Celecoxib, which I take once daily.
However, I have peripheral circulation issues, so my family bought Circulating Ning for me to take.
I noticed in the precautions that it should not be used in conjunction with non-steroidal anti-inflammatory drugs.
Would it be safe to take them with a gap of one or two hours? Additionally, I am also taking traditional Chinese medicine for promoting blood circulation and relieving stasis.
I am unsure if these medications will interact with Circulating Ning.
If there is an interaction, should I stop taking them, or can I take them two hours apart?

Huang Huiqi, 40~49 year old female. Ask Date: 2022/12/10

Dr. Huang Shenggang reply Pharmacology


Hello Ms.
Huang: Thank you for your inquiry.
Regarding the simultaneous use of Xunli Ning and the non-steroidal anti-inflammatory drug Celebrex, you can ask your doctor for an evaluation and prescription, as Xunli Ning is also available in hospitals.
The main reasons for caution are that some individuals may experience side effects that could lead to bleeding, so it is generally advised not to use them together to avoid increasing the risk of bleeding.
Additionally, if you are taking traditional Chinese medicine that promotes blood circulation and removes blood stasis, please inform your Chinese medicine practitioner that you are using Xunli Ning for further assessment.
There is no need to worry too much.
Thank you for your question.

Reply Date: 2022/12/10

More Info


When it comes to understanding the contraindications and potential interactions of medications, it is crucial to consider both the pharmacological properties of the drugs involved and the specific health conditions of the patient. In your case, you are currently taking a non-steroidal anti-inflammatory drug (NSAID) called Celecoxib (希樂葆) for pain management following spinal surgery, and you are also considering taking Circulating Medications (循立寧) due to peripheral circulation issues.
Firstly, it is important to note that NSAIDs like Celecoxib are commonly used for their analgesic and anti-inflammatory properties. However, they can have side effects, particularly on the gastrointestinal tract, kidneys, and cardiovascular system. The use of NSAIDs is generally contraindicated in patients with certain conditions, such as active gastrointestinal bleeding, severe renal impairment, or a history of cardiovascular events, among others.

On the other hand, Circulating Medications (循立寧) are often used to improve blood circulation and may have specific contraindications when used in conjunction with NSAIDs. The caution against using these two classes of medications together typically stems from the potential for increased risk of adverse effects, particularly gastrointestinal issues. The concern is that both medications can affect blood flow and clotting mechanisms, which could lead to complications, especially in patients with underlying health issues.

Regarding your question about spacing the doses of these medications, it is generally advisable to consult your healthcare provider before making any changes to your medication regimen. While spacing the doses by a couple of hours may reduce the likelihood of interaction, it does not eliminate the risk entirely. The pharmacokinetics of each drug, including how they are absorbed, metabolized, and excreted, can vary significantly between individuals, and this can influence the effectiveness and safety of the medications when taken together.

Additionally, you mentioned that you are also taking traditional Chinese medicine (TCM) for blood circulation and muscle relaxation. TCM can have various effects on the body, and its interactions with Western medications can be complex. Some herbal ingredients may enhance the effects of NSAIDs or Circulating Medications, while others may counteract their effects or increase the risk of side effects. For example, certain herbs may have anticoagulant properties, which could increase the risk of bleeding when combined with NSAIDs.

In summary, while it may be tempting to space out the doses of Celecoxib and Circulating Medications, the safest approach is to consult your healthcare provider. They can provide personalized advice based on your overall health status, the specific medications you are taking, and any potential interactions with the TCM you are using. It is essential to have an open dialogue with your healthcare team about all medications and supplements you are taking to ensure safe and effective treatment. Always prioritize safety and seek professional guidance when managing multiple medications.

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