Hemoptysis After Lung Adenocarcinoma Surgery: What to Know - Pulmonology

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Pulmonary adenocarcinoma with hemoptysis?


Your question: Hello, I am a stage 3B lung adenocarcinoma patient currently undergoing treatment with Anlotinib.
I had surgery on November 3rd, and it has been almost two months since the operation.
Recently, I have noticed a small amount of blood in my cough when I wake up in the morning.
I just had a CT scan on December 1st, which showed no deterioration.
Is this a cause for concern? Is it normal? Why is this happening? Is it related to the surgery, the cold weather, disease progression, or a reaction to the medication? Thank you for your response, doctor.

Xiao Ke, 40~49 year old female. Ask Date: 2022/12/26

Dr. Huang Yiwen reply Pulmonology


Dear Xiao Ke: Taking Alectinib is appropriate for cases of ALK-positive lung adenocarcinoma.
After surgery, having just completed a CT scan with no signs of deterioration suggests that it is likely not a progression of the disease.
It could be caused by a cough leading to minor pulmonary microvascular rupture.
Please avoid overly spicy foods and continue to monitor your condition.
Changhua Hospital cares about you.

Reply Date: 2022/12/26

More Info


Hemoptysis, or coughing up blood, can be a concerning symptom for patients who have undergone lung surgery, particularly for those with a history of lung adenocarcinoma. In your case, having had surgery for stage 3B lung adenocarcinoma and currently undergoing treatment with targeted therapy (such as Anlotinib), it is understandable to be anxious about the presence of blood in your cough.

Firstly, it is important to consider the timing of your surgery. Surgical procedures on the lungs can lead to various postoperative complications, including irritation of the airways, inflammation, or even minor bleeding from the surgical site. The presence of blood-streaked sputum, especially if it is minimal and occurs intermittently, may not be unusual in the weeks following surgery. This could be due to residual irritation from the surgical manipulation of lung tissue or the healing process itself.

Additionally, environmental factors such as cold weather can exacerbate respiratory symptoms. Cold air can lead to bronchial irritation, which may cause coughing and, in some cases, minor bleeding. If you have been experiencing dry air or significant temperature changes, this could also contribute to your symptoms.

It is also worth noting that while the recent CT scan showed no signs of disease progression, it is crucial to remain vigilant. Hemoptysis can sometimes indicate underlying issues such as infection, inflammation, or, in rare cases, tumor recurrence. However, given that your CT scan did not show any worsening of your condition, it is less likely that the hemoptysis is related to cancer progression at this time.

Regarding your concerns about the medication, Anlotinib is a targeted therapy that can have side effects, including potential effects on the respiratory system. However, significant hemoptysis is not a common side effect of this medication. If you suspect that your symptoms might be related to the medication, it is essential to discuss this with your oncologist.

In summary, while the presence of blood in your cough after lung surgery can be alarming, it is not always indicative of a serious problem, especially if it is minimal and your recent imaging shows no signs of worsening disease. However, it is crucial to monitor your symptoms closely. If the hemoptysis persists, increases in volume, or is accompanied by other concerning symptoms (such as fever, increased shortness of breath, or chest pain), you should contact your healthcare provider promptly. They may recommend further evaluation, which could include repeat imaging or a bronchoscopy to assess the airways directly.

In conclusion, while some degree of hemoptysis can be expected post-surgery, especially in the context of lung cancer treatment, it is essential to maintain open communication with your healthcare team. Regular follow-ups and discussions about any new or worsening symptoms will help ensure that any potential issues are addressed promptly and effectively.

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