Is Bruising After Moderna Bivalent Vaccine a Normal Reaction? - Family Medicine

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After receiving the Moderna bivalent next-generation vaccine, there was bruising?


Hello Doctor: My mother, who is 66 years old, noticed a bruise at the injection site three days after receiving the Moderna bivalent next-generation vaccine.
Is this a normal reaction? Will it resolve on its own? Thank you, Doctor!

Niming, 60~69 year old female. Ask Date: 2023/01/06

Dr. Lin Zhebin reply Family Medicine


Hello: During vaccination, it is possible to injure the local microvasculature, leading to bruising.
Generally, this will resolve on its own.
However, if the bruise continues to enlarge, there is severe swelling and pain, the appearance of other bruises on the body, difficulty breathing, or chest discomfort, it is advised to seek medical attention immediately.

Reply Date: 2023/01/06

More Info


Bruising after receiving a vaccine, including the Moderna bivalent vaccine, can be a normal reaction. Vaccines are administered via intramuscular injection, which can sometimes cause minor trauma to the blood vessels in the area, leading to localized bleeding and subsequent bruising. This is particularly common in older adults, as their skin and blood vessels may be more fragile.

In most cases, the bruise will resolve on its own within a week or two. The body will naturally reabsorb the blood that has leaked into the surrounding tissue, and the bruise will change colors as it heals, typically transitioning from red or purple to yellow or green before disappearing completely. It is important to monitor the bruise for any signs of complications, such as increased swelling, redness, warmth, or pain, which could indicate an infection or other issues.

If your mother is otherwise feeling well and does not exhibit any severe symptoms, there is generally no cause for concern regarding the bruise. However, if she experiences significant discomfort or if the bruise does not improve over time, it would be advisable to consult a healthcare professional for further evaluation.

In addition to bruising, other common side effects of the Moderna vaccine can include pain at the injection site, fatigue, headache, muscle pain, chills, fever, and joint pain. These reactions are typically mild to moderate and resolve within a few days. They are indicative of the immune system responding to the vaccine and building protection against the virus.

It's also worth noting that individuals with certain medical conditions or those taking medications that affect blood clotting may be more prone to bruising. If your mother has a history of bleeding disorders or is on anticoagulant therapy, it may be prudent to discuss her vaccination experience with her healthcare provider.

In summary, bruising after receiving the Moderna bivalent vaccine can be a normal reaction and should resolve on its own. However, if there are any concerns about the bruise or if your mother experiences any unusual symptoms, seeking medical advice is always a good practice.

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