Retinal Degeneration and Night Blindness: Key Insights - Ophthalmology

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Eye degeneration, retinal degeneration, night blindness?


Hello Doctor, I recently visited a large hospital for an eye examination.
I underwent dark adaptation tests, visual field tests, and OCT, and I was diagnosed with retinal dystrophy.
I've felt that my night vision has been worse than others for a long time, but no one in my family has night blindness.
My father seems to have some color blindness, but my brother and mother do not.
The examination showed that only the central part of my retina is healthy, while the peripheral areas are abnormal.
There are not many photoreceptor cells, so I have difficulty seeing in the dark peripherally.
The doctor mentioned that this condition may worsen with age and could eventually lead to cataracts, advising me to be cautious of UV exposure and to consume more lutein.
I need to undergo genetic testing and electrophysiological examinations to identify which gene is involved, and then continue monitoring my condition.

I suddenly forgot to ask the doctor the following questions: Since I am only 22 years old, am I at risk of rapid deterioration, and is there a 100% chance that this night blindness will lead to blindness in the future? Additionally, I have recently developed floaters.
Could this be related? I noticed that when I look at the sky or bright lights, I see flashes of light that feel a bit dazzling, but they go away after a while.
Is this due to photophobia? (I have also been experiencing some sleep deprivation and eye strain lately; could this have an impact?) Thank you.

Ms. Hsieh, 20~29 year old female. Ask Date: 2023/01/17

Dr. Gao Pilin reply Ophthalmology


Hello: Is it true that night blindness will inevitably lead to complete blindness in the future? It's not that pessimistic.
According to large-scale statistics, it is rare for retinitis pigmentosa to cause total vision loss; approximately 20% of individuals may have monocular vision below 0.1.
However, half of the individuals over the age of 60 still maintain at least monocular vision of 0.5 or higher.
Please refer to: https://bit.ly/3WevliD.
Floaters are not related to night blindness, and photophobia is a symptom that can occur when the eyes are inflamed, uncomfortable, overly fatigued, or dry.

Reply Date: 2023/01/17

More Info


Understanding retinal degeneration and night blindness is crucial for anyone experiencing vision issues, especially at a young age like 22. Your concerns about retinal degeneration, night blindness, and the recent onset of floaters are valid and deserve careful consideration.

Firstly, it’s important to clarify that night blindness, or nyctalopia, is not a condition that guarantees complete blindness in the future. While certain retinal degenerative diseases can lead to significant vision loss, statistics indicate that not everyone with retinal degeneration will experience total vision loss. For example, studies show that a significant portion of individuals with conditions like retinitis pigmentosa maintain some level of vision into their later years. The fear of inevitable blindness can be daunting, but it’s essential to focus on regular monitoring and management of your condition.

Regarding your family history, it’s interesting to note that while color blindness (which your father has) and night blindness can both have genetic components, they are distinct conditions. Color blindness primarily affects the ability to perceive colors, while night blindness is related to the function of rod photoreceptors in the retina, which are responsible for vision in low-light conditions. The absence of night blindness in your family does not rule out the possibility of developing it yourself, especially if it is linked to a genetic mutation that may not have manifested in your relatives.

The relationship between retinal degeneration and floaters is also noteworthy. Floaters are typically caused by changes in the vitreous gel of the eye, which can occur with age or due to retinal changes. While floaters themselves are generally benign, their sudden increase can sometimes indicate retinal issues, particularly if accompanied by flashes of light or a shadow in your peripheral vision. It’s good that you’ve had a thorough examination to rule out serious conditions, but keep monitoring any changes in your symptoms.

Your experience of seeing halos around lights and sensitivity to bright lights (photophobia) could be related to several factors, including fatigue, dry eyes, or even the effects of retinal degeneration. Sleep deprivation can exacerbate eye strain and lead to temporary visual disturbances. Ensuring you get adequate rest and managing screen time can help alleviate some of these symptoms.

As for the advice you received regarding UV protection and dietary supplements like lutein, these are indeed beneficial for eye health. Lutein and zeaxanthin are carotenoids that can help filter harmful blue light and may support retinal health. Regular eye exams and possibly genetic testing, as suggested by your doctor, can provide more personalized insights into your condition and help in monitoring any progression.

In summary, while your concerns about night blindness and retinal degeneration are valid, it’s essential to approach them with a balanced perspective. Regular follow-ups with your eye care professional, maintaining a healthy lifestyle, and being proactive about your eye health can significantly impact your quality of life and visual function. If you notice any new symptoms or changes, don’t hesitate to reach out to your healthcare provider for further evaluation.

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