Factors Affecting Urine Test Results: Protein and Blood Levels - Family Medicine

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I would like to inquire about the factors that can affect urine test results?


Medical Examination Report: Urine: Protein 15 mg/dL, Albumin 80 mg/dL, Occult blood 1+; Blood: Glucose 81 mg/dL.
The urine test was conducted in the morning of the examination day, but it was discovered in the afternoon that menstruation had started.
The presence of occult blood in the urine is likely influenced by menstruation, but could the urine protein levels also be affected by the menstrual cycle? Since the fasting blood glucose is within the normal range, I am unsure if a follow-up with a metabolic specialist is necessary.
Thank you, doctor, for your patient response.

Miss Zhang, 20~29 year old female. Ask Date: 2023/01/18

Dr. Ye Qianyu reply Family Medicine


Hello! It is recommended that you have a follow-up examination one week after your menstrual period ends.
You can choose either general internal medicine or family medicine for the consultation.

Reply Date: 2023/01/18

More Info


When interpreting urine test results, particularly regarding protein and blood levels, it is essential to consider various factors that can influence these measurements. In your case, you have reported urine protein levels of 15 mg/dL and albumin levels of 80 mg/dL, along with a positive occult blood test (1+). Additionally, you mentioned that you started your menstrual period in the afternoon after your morning urine test.
Firstly, it is important to understand the significance of protein in urine. Normally, urine should contain very little protein, as the kidneys filter out most proteins from the blood. A urine protein level of 15 mg/dL is generally considered low and may not be clinically significant. However, the presence of albumin (a type of protein) at 80 mg/dL is noteworthy. Elevated levels of albumin in urine can indicate kidney damage or disease, particularly if the levels are consistently high over time. This condition is often referred to as albuminuria and can be an early sign of kidney disease, especially in individuals with risk factors such as diabetes or hypertension.

Regarding the positive occult blood test, it is crucial to consider that menstruation can indeed affect urine test results. The presence of blood in urine (hematuria) can be due to various reasons, including urinary tract infections, kidney stones, or trauma, but in your case, it is likely influenced by your menstrual cycle. It is advisable to repeat the urine test after your menstrual period to obtain a more accurate assessment of your urinary health.

As for the impact of your menstrual cycle on urine protein levels, it is less common for menstruation to significantly affect protein levels in urine. However, hormonal changes during the menstrual cycle can influence kidney function and fluid balance, which may lead to temporary fluctuations in protein levels. Therefore, while it is unlikely that your menstrual cycle is the sole cause of the protein level you reported, it is still a good practice to monitor these levels over time, especially if you have any underlying health conditions.

In terms of your fasting blood glucose level being within the normal range, this is a positive sign and suggests that your glucose metabolism is functioning adequately at this time. However, if you have concerns about your metabolic health or if there are other risk factors present, it may be beneficial to follow up with a specialist, such as an endocrinologist or a metabolic health expert, for further evaluation and management.

In summary, while your urine protein level of 15 mg/dL is low and may not be a cause for concern, the elevated albumin level warrants further investigation. The positive occult blood test is likely influenced by your menstrual cycle, and it is advisable to repeat the urine test after your period. Regular monitoring and consultation with healthcare professionals will help ensure that any potential issues are addressed promptly. If you have any additional symptoms or concerns, do not hesitate to reach out to your healthcare provider for further guidance.

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