Post-Treatment Lifestyle and Concerns for Syphilis Patients - Urology

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Lifestyle and Treatment Outcomes for Patients with Syphilis After Treatment


Hello, doctor.
I completed a penicillin treatment for syphilis a month ago, and I haven't noticed any ulcers or rashes in the affected area.
In your previous article, you mentioned that one can return to normal life after treatment.
Does "after treatment" refer to after receiving the injection or after confirming complete cure? Since I live with my partner, can we engage in the following activities considered "normal life"? 1.
Holding hands 2.
Hugging 3.
Kissing 4.
Washing clothes together 5.
Eating together 6.
Having protected sexual intercourse.
Are there any activities that you would advise against?
Another question: my doctor in the United States confidently told me that after the injection, the titers can only decrease, and if they increase, it indicates a new infection leading to a relapse.
He assured me that I could fully enjoy a normal married life.
This seems to differ from the information I received domestically.
Is this truly the medical consensus? Thank you for your response.

Yao, 30~39 year old female. Ask Date: 2023/02/04

Dr. Du Shixi reply Urology


Hello: It is acceptable to engage in sexual activity once blood tests return normal, and it is also possible to practice safe sex for a period of time.
The primary focus with syphilis is regular monitoring; however, regardless of whether in Taiwan or abroad, blood follow-up is necessary.
An increase in titers could indicate either reinfection or treatment failure, and it can be difficult for physicians to determine whether it is a case of reinfection or treatment failure.
If such a situation is discovered, re-treatment is required.

In terms of categorizing sexual activity by risk level, no-risk activities include masturbation, hugging, and touching areas other than the genitals; low-risk activities include mutual masturbation, light kissing, mutual rubbing, and sexual intercourse with condoms; moderate-risk activities include deep kissing, oral sex, and withdrawal before ejaculation; while high-risk activities include unprotected intercourse and intercourse that causes wounds or bleeding.

Reply Date: 2023/02/04

More Info


After completing treatment for syphilis with penicillin, it is understandable to have questions about what constitutes a "normal" lifestyle post-treatment, especially regarding interactions with your partner. Let's address your concerns step by step.

Firstly, the term "post-treatment" generally refers to the period after you have received the full course of treatment, which in your case is the administration of penicillin. However, it is crucial to confirm that the treatment has been effective, which is typically done through follow-up blood tests to check for a decrease in the titers of the syphilis antibodies (e.g., RPR or VDRL tests). A significant drop in these titers indicates that the infection is being treated successfully. It is advisable to wait for these results before fully resuming all intimate activities.

Now, regarding your specific questions about physical interactions with your partner:
1. Holding Hands: This is perfectly safe and poses no risk of transmission.

2. Hugging: Similarly, hugging is safe and does not pose a risk.

3. Kissing: Kissing is generally safe as long as there are no active sores or lesions present in the mouth or on the lips.

4. Washing Clothes Together: This is also safe. Syphilis is not transmitted through casual contact or shared items.

5. Eating Together: Sharing food is safe as long as there are no open sores or lesions.

6. Sexual Intercourse: Engaging in sexual activities is safe if you use protection (condoms) and both partners are aware of their sexual health status. It is advisable to wait until follow-up tests confirm that the infection has been cleared before resuming unprotected sexual activities.

As for your second question regarding the medical consensus on post-treatment behavior, it is important to note that while the risk of transmission decreases significantly after successful treatment, it does not become zero immediately. The advice from your doctor in the U.S. that a rise in titers indicates a new infection is consistent with medical understanding. If titers rise after treatment, it suggests either a reinfection or that the initial treatment was not effective. Therefore, it is crucial to have follow-up testing to ensure that the treatment was successful.

In summary, while you can resume many normal activities after treatment, it is best to wait for confirmation of cure through follow-up blood tests before fully engaging in intimate activities, especially unprotected sex. Always communicate openly with your partner about your health status and any concerns you may have. If you have further questions or uncertainties, it is advisable to consult your healthcare provider for personalized guidance based on your specific situation.

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