Effective Treatments for Anal Warts: Options and Considerations - Surgery

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Treatment for anal warts?


Hello, doctor.
About two years ago, I had warts in my anal area, which were treated with medication and cryotherapy, and they resolved.
However, last month I noticed a recurrence, with one or two new growths in the same area.
I applied Aldara (a topical imiquimod cream) along with cryotherapy, but although there was some skin reaction, the warts did not fall off.
During a self-examination at home, I suspected that there might also be growths inside the anal canal, but when I visited a dermatologist for cryotherapy, the doctor checked and said there were none.
Since the cryotherapy has not been effective, the doctor suspects that it may not be warts (he mentioned that warts usually do not grow this large) and advised me to continue using Aldara for another week to see if they resolve.
If not, he suggested I consult a colorectal surgeon.
I would like to ask you, when I apply the cream, I experience skin reactions.
As I understand, the mechanism of Aldara is to stimulate the immune cells to attack the virus, so if it is not warts, there should not be any reaction, correct? Additionally, if the growths inside the anal canal are indeed warts, can they be treated with cryotherapy or laser therapy, or is electrosurgery the only option for internal lesions? I am mainly concerned about the recovery time affecting my work.
Thank you for your response.

K, 20~29 year old female. Ask Date: 2023/02/09

Dr. Zhang Shuhao reply Surgery


Current antiviral ointments, including Acyclovir, can cause irritation to the skin, resulting in redness, swelling, and burning sensations, even in areas not affected by warts.
Warts located within the anal canal typically require examination with an anoscope, making it difficult to treat with ointments, cryotherapy, or laser therapy, especially for larger lesions.
It is recommended to remove them via electrosurgery.
The recovery period is approximately 1-2 weeks, and the level of discomfort post-procedure is similar to that experienced with topical ointments, generally not affecting one's ability to work.

Reply Date: 2023/02/09

More Info


Anal warts, also known as condylomata acuminata, are caused by the human papillomavirus (HPV) and can be a source of discomfort and concern for many individuals. The recurrence of anal warts, as you've experienced, is not uncommon, and there are several treatment options available that can be effective in managing this condition.


Treatment Options for Anal Warts
1. Topical Treatments:
- Imiquimod (Aldara): This is an immune response modifier that helps the body fight the HPV virus. It is applied directly to the warts and can cause local irritation, which is a sign that the immune system is responding.
- Podophyllin and Podofilox: These are cytotoxic agents that destroy wart tissue. They are typically applied by a healthcare provider, but Podofilox can also be used at home. Side effects may include irritation and pain at the application site.

- Sinecatechins (Veregen): This is a green tea extract that can be used for external warts. It works by stimulating the immune response.

2. Cryotherapy:
- This involves freezing the warts with liquid nitrogen. It is a common treatment method and can be effective, but multiple sessions may be required. The fact that you experienced a skin reaction indicates that the treatment was working, but it may not always lead to complete resolution of the warts.

3. Laser Therapy:
- Laser treatment can be effective for larger or more persistent warts. It uses focused light to destroy wart tissue. This method is generally well-tolerated, but it can be more expensive and may require local anesthesia.

4. Electrosurgery:
- This technique uses electrical currents to burn off the warts. It can be effective for warts that are difficult to treat with other methods. However, it may involve a longer recovery time and can be painful.

5. Surgical Excision:
- In cases where warts are particularly large or resistant to other treatments, surgical removal may be necessary. This is usually done under local anesthesia.


Considerations for Treatment
- Diagnosis Confirmation: It’s crucial to ensure that the growths are indeed anal warts. If there is any doubt, a biopsy may be warranted to rule out other conditions, including anal fissures or even more serious issues like anal cancer.


- Follow-Up Care: Regardless of the treatment chosen, follow-up appointments are essential to monitor for recurrence. HPV can remain dormant in the body, and warts can reappear even after successful treatment.

- Impact on Daily Life: You mentioned concerns about recovery time affecting your work. Treatments like topical medications may allow for more flexibility, while procedures like electrosurgery or laser therapy may require more downtime. Discussing your work schedule with your healthcare provider can help tailor a treatment plan that minimizes disruption.

- Immune Response: As you noted, treatments like Imiquimod work by stimulating the immune system. If the lesions are not responding to treatment, it may indicate that they are not caused by HPV or that a different treatment approach is needed.


Conclusion
In summary, anal warts can be effectively treated through various methods, including topical treatments, cryotherapy, laser therapy, and surgical options. It’s essential to have a thorough evaluation to confirm the diagnosis and to discuss the most appropriate treatment plan with your healthcare provider. If the current treatment is not yielding results, seeking a second opinion or further evaluation by a colorectal specialist may be beneficial. Remember to communicate openly with your healthcare team about your concerns and the impact of treatment on your daily life.

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