Lung Nodules: When to Consider Surgical Removal? - Pulmonology

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The concerns of pulmonary nodules?


Hello, Director Huang.
I was diagnosed with stage I nasopharyngeal carcinoma in January 2022.
A PET scan showed normal lungs, but during a follow-up CT in December 2022, a 0.8 x 1.3 mm oval non-solid nodule was found in the right lung.
A bronchoscopy biopsy was performed, and no abnormalities were detected.
The doctor mentioned that this was due to random sampling from the lung.
Is it because the endoscope cannot obtain precise samples? Currently, I am taking antibiotics for five days, and I will have another CT scan on February 9.
May I ask, if the size remains unchanged, would you recommend direct resection in this situation? Thank you for your valuable time.

Xia, 30~39 year old female. Ask Date: 2023/02/13

Dr. Huang Yiwen reply Pulmonology


Dear Xia: It is recommended to proceed with direct excision.
Currently, thoracoscopic surgery is very convenient and safe.
A 1.3 mm excision would provide more peace of mind.
Changhua Hospital cares about you.

Reply Date: 2023/02/13

More Info


Understanding lung nodules is crucial, especially for patients with a history of cancer, such as your case of nasopharyngeal carcinoma. Lung nodules are small masses of tissue in the lung that can be benign or malignant. The management of these nodules often depends on several factors, including the size, shape, growth rate, and the patient's overall health and history.

In your situation, you have a 0.8 x 1.3 cm oval, non-solid nodule in the right lung, which was identified during a follow-up CT scan. The fact that a bronchoscopy was performed and no abnormalities were found is reassuring, but it does raise questions about the nature of the nodule. Bronchoscopy can sometimes miss lesions, particularly if they are small or located in areas that are difficult to access. This is why follow-up imaging is often recommended.

The decision to consider surgical removal of a lung nodule typically hinges on several criteria:
1. Size and Growth: Nodules that are larger than 1 cm and show growth over time are more concerning for malignancy. In your case, since the nodule is still relatively small and has not shown any growth, this may suggest a lower risk of cancer.

2. Imaging Characteristics: The characteristics of the nodule on imaging studies (CT scans) can provide valuable information. Non-solid nodules, especially those that are stable in size over time, are often less likely to be cancerous. However, the specific features of the nodule, such as its margins and density, can influence the decision.

3. Patient History: Your history of nasopharyngeal carcinoma is significant. Patients with a history of cancer are at a higher risk for developing secondary malignancies, including lung cancer. This history may necessitate a more cautious approach, even if the nodule appears benign.

4. Follow-Up Protocol: The current standard of care often involves a watchful waiting approach with regular imaging follow-ups for nodules that are stable in size and without concerning features. If your nodule remains unchanged after a set period (often 3-6 months), further intervention may be reconsidered.

5. Surgical Risks vs. Benefits: If the nodule is suspected to be malignant or if there is significant concern based on your medical history, surgical removal may be warranted. However, surgery carries its own risks, especially in patients with a history of cancer or other comorbidities.

In your case, since the nodule has not changed in size and given the results of the bronchoscopy, it may not be immediately necessary to proceed with surgical removal. However, close monitoring with follow-up CT scans is essential. If there are any changes in size or characteristics, or if you develop new symptoms, further evaluation would be warranted.

In conclusion, while surgical removal of lung nodules can be a definitive treatment, it is essential to weigh the risks and benefits carefully. Regular follow-up imaging and consultations with your healthcare team will help ensure that any changes in your condition are addressed promptly. Always feel free to discuss your concerns and preferences with your oncologist, as they can provide personalized recommendations based on your specific situation.

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