Is XET 20mg Safe? Its Effects on Mental Health - Psychiatry

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Will taking XET 20mg harm my health?


Hello Doctor: I have been seeing a psychiatrist for severe panic disorder for two years.
Recently, I was laid off due to company politics, which has led to deep feelings of guilt and resentment.
Every time I interview for a new job, I have to briefly explain the reason for my departure, which brings back these unpleasant memories.
The doctor prescribed me XET 20mg tablets, but after taking them for two days, my mood hasn't improved, and I've been experiencing diarrhea.
Should I continue taking it? Additionally, I would like to know if this medication can harm my body and whether it is metabolized by the liver or the kidneys.
Thank you.

Qiqi, 30~39 year old female. Ask Date: 2023/02/16

Dr. Qiu Junda reply Psychiatry


Hello.
XET 20mg is an antidepressant.
Generally, it takes more than two weeks to see if it is effective.
It often has gastrointestinal side effects, but after a few days of use, one can gradually adapt and improve.
It is not harmful to the body and is metabolized by the liver.
If the side effects are truly intolerable, you can return to the clinic to discuss adjustments with your physician.

Reply Date: 2023/02/16

More Info


XET 20mg, which is likely a reference to the antidepressant medication Escitalopram, is commonly prescribed for conditions such as severe panic disorder and generalized anxiety disorder. Understanding its safety and effects on mental health is crucial, especially for individuals who have been dealing with significant emotional distress, as in your case.


Safety and Side Effects
Escitalopram, like other selective serotonin reuptake inhibitors (SSRIs), works by increasing the levels of serotonin in the brain, which can help improve mood and reduce anxiety. While many patients experience positive outcomes, it is important to note that side effects can occur. Common side effects include gastrointestinal issues such as nausea, diarrhea, and changes in appetite, which you have experienced as diarrhea. Other potential side effects may include insomnia, fatigue, sexual dysfunction, and increased anxiety during the initial treatment phase.

It is not uncommon for patients to feel that their mood has not improved after just a couple of days on the medication. SSRIs typically require a few weeks (often 4-6 weeks) to reach their full therapeutic effect. Therefore, it is essential to give the medication some time to work, unless the side effects are intolerable.


Should You Continue Taking It?
If the diarrhea is persistent and bothersome, it is advisable to consult your prescribing physician. They may suggest continuing the medication for a bit longer to see if your body adjusts to it, or they might consider adjusting the dosage or switching to a different medication. It is crucial not to stop or adjust the medication without consulting your doctor, as this can lead to withdrawal symptoms or a worsening of your condition.


Metabolism of XET
Regarding the metabolism of XET (Escitalopram), it is primarily metabolized in the liver. The liver enzymes, particularly CYP2C19 and CYP3A4, play a significant role in breaking down the medication. This is important to consider, especially if you have any liver conditions or are taking other medications that may affect liver function. The kidneys also play a role in excreting the metabolites, but the primary metabolic pathway is hepatic.


Long-term Considerations
While Escitalopram is generally considered safe for most patients, long-term use should be monitored by a healthcare professional. Regular follow-ups can help assess the effectiveness of the treatment and any potential side effects. If you have concerns about dependency or long-term effects, discussing these with your doctor can provide clarity and reassurance.


Conclusion
In summary, XET 20mg can be a safe and effective treatment for panic disorder, but it may come with side effects that need to be managed. It is essential to give the medication time to work while maintaining open communication with your healthcare provider about any side effects you experience. Your mental health is paramount, and your doctor can help you navigate the best course of action for your treatment. If you continue to experience significant side effects or if your mood does not improve, do not hesitate to reach out to your healthcare provider for further evaluation and support.

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