Does Daily Use of Xanax and Interal Harm Your Body? - Psychiatry

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Will taking psychiatric medications daily cause harm to the body?


Pathology Introduction: The patient has been suffering from a neurosis (agoraphobia) for 5 years and currently must take Xanax (0.5 mg) and Interal (10 mg) at half a tablet each daily to maintain normal social activities.
If discontinued, there will be a strong recurrence of panic attacks within 3 days.
The triggers for panic attacks occur in situations where the patient cannot move freely (e.g., during meetings, classes, or while using public transportation).
I would like to ask: 1.
Will long-term use of Xanax (0.5 mg) and Interal (10 mg) (once daily, half a tablet each) cause any harm to the body (e.g., liver or kidneys)? 2.
Are there any medications for treating panic disorder that are more effective than Xanax (0.5 mg)? Thank you for your response!

Miao, 20~29 year old female. Ask Date: 2005/07/06

Dr. Wang Chongren reply Psychiatry


Dear Dr.
Wang Chong-Ren of the Tainan Hospital, Department of Psychiatry, Executive Yuan Health Department:
Based on your description, you may be experiencing panic disorder combined with agoraphobia.
Since this has become chronic, you may have anticipatory anxiety in situations you mentioned that are prone to triggering episodes, leading to maladaptive avoidance behaviors.
Currently, your medication dosage is low and should not cause significant liver or kidney side effects.
You may consider using a new generation antidepressant or combining it with cognitive behavioral therapy to improve excessive anticipatory anxiety and avoidance behaviors.

Wishing you good health and all the best from the Department of Psychiatry, Tainan Hospital.

Reply Date: 2005/07/06

More Info


The use of Xanax (alprazolam) and Inderal (propranolol) for managing anxiety and panic disorders can be effective, but it also raises concerns about long-term health effects and potential dependency. Let's address your questions regarding the long-term use of these medications and explore alternative treatment options for panic disorder.


Long-Term Use of Xanax and Inderal
1. Potential Harm to the Body:
- Xanax: Long-term use of Xanax can lead to physical dependence and tolerance. This means that over time, you may require higher doses to achieve the same therapeutic effect. Withdrawal symptoms can occur if the medication is abruptly discontinued, which can include increased anxiety, panic attacks, insomnia, and physical symptoms like sweating and tremors. Xanax is metabolized by the liver, and while it is generally safe for most individuals when taken as prescribed, chronic use can potentially stress the liver, especially if combined with other substances that affect liver function (like alcohol).

- Inderal: Propranolol is a beta-blocker that is often used to manage physical symptoms of anxiety, such as rapid heartbeat and tremors. It is generally considered safe for long-term use, but it can have side effects, including fatigue, dizziness, and gastrointestinal issues. It is also important to monitor heart rate and blood pressure regularly, as propranolol can lower both.

2. Impact on Organs:
- Both medications can affect the liver and kidneys, but significant damage is unlikely if they are used as prescribed and monitored by a healthcare provider. Regular check-ups and blood tests can help ensure that your liver and kidney functions remain normal while on these medications.


Alternative Treatments for Panic Disorder
While Xanax can be effective for short-term relief of panic symptoms, there are other treatment options that may be more suitable for long-term management of panic disorder:
1. Selective Serotonin Reuptake Inhibitors (SSRIs): Medications like sertraline (Zoloft) or fluoxetine (Prozac) are often first-line treatments for panic disorder. They work by increasing serotonin levels in the brain, which can help improve mood and reduce anxiety over time.

2. Cognitive Behavioral Therapy (CBT): This is a highly effective form of psychotherapy for panic disorder. CBT helps individuals understand and change their thought patterns and behaviors that contribute to anxiety and panic attacks. It often includes exposure therapy, where patients gradually face their fears in a controlled environment.

3. Lifestyle Modifications: Regular exercise, a healthy diet, adequate sleep, and mindfulness practices such as meditation or yoga can significantly reduce anxiety symptoms and improve overall mental health.

4. Other Medications: If Xanax is not suitable for long-term use, other medications such as buspirone or certain antidepressants may be considered. These alternatives can provide anxiety relief without the same risk of dependence.


Conclusion
In summary, while daily use of Xanax and Inderal can be effective for managing panic disorder, it is essential to be aware of the potential risks associated with long-term use. Regular monitoring by a healthcare professional is crucial to ensure that your liver and kidney functions remain healthy. Additionally, exploring alternative treatments such as SSRIs, CBT, and lifestyle changes can provide a more sustainable approach to managing panic disorder without the risks associated with benzodiazepines like Xanax. Always consult with your healthcare provider before making any changes to your medication regimen or treatment plan.

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