Impact of Clindamycin Vaginal Gel on Pregnancy: Safety and Concerns - Obstetrics and Gynecology

Share to:

Lomefloxacin vaginal gel


Hello, I am currently about 35 weeks pregnant and have noticed some discharge (yellow-green in color) with a slight odor.
I informed my doctor during my prenatal check-up, and they prescribed Clindamycin vaginal suppositories.
Will this have any impact on the fetus? Will the medication remain in the vagina and not be absorbed? Do these suppositories dissolve and get absorbed once inserted into the vagina? The doctor prescribed a 6-day course, and since this is my first time using such a suppository, I am concerned about whether it will break down and not leave any residue in the vagina, which could be harmful to me and my baby.

Si Mo, 20~29 year old female. Ask Date: 2023/02/20

Dr. Lin Manying reply Obstetrics and Gynecology


Hello, it is recommended to consult your original attending physician for the best advice.
Hualien Hospital, Ministry of Health and Welfare, cares about your health.

Reply Date: 2023/02/20

More Info


Clindamycin vaginal gel is a medication often prescribed for bacterial infections, including bacterial vaginosis, which can occur during pregnancy. When considering the safety of any medication during pregnancy, it is crucial to evaluate both the potential risks to the fetus and the benefits of treating the mother's condition.

Clindamycin is classified as a Category B drug by the FDA, which means that animal reproduction studies have not shown a risk to the fetus, and there are no adequate and well-controlled studies in pregnant women. This classification suggests that Clindamycin is generally considered safe for use during pregnancy, particularly when prescribed by a healthcare provider for a specific condition. However, it is always essential to use medications only when necessary and under the guidance of a healthcare professional.

Regarding your concerns about the gel's absorption and potential residue, Clindamycin vaginal gel is designed to be inserted into the vagina, where it will dissolve and be absorbed by the tissues. The gel formulation allows for localized treatment, meaning that it primarily acts at the site of application and is less likely to enter the systemic circulation in significant amounts. This localized action minimizes the risk of systemic side effects and potential impacts on the developing fetus.

When you insert the gel, it will indeed soften and break down, allowing the active ingredient to be absorbed effectively. The gel is formulated to ensure that it does not leave significant residue that could cause irritation or other issues. However, it is essential to follow the instructions provided by your healthcare provider regarding the application and duration of treatment.

As for your concerns about the potential impact on your baby, the use of Clindamycin vaginal gel in the recommended manner is unlikely to pose a risk to fetal development. The benefits of treating an infection, such as preventing complications that could arise from untreated bacterial vaginosis, generally outweigh the risks associated with the medication. Untreated infections during pregnancy can lead to more severe outcomes, including preterm labor or low birth weight, so it is crucial to address any infections promptly.

If you have any lingering concerns about the medication or its effects, it is always best to discuss them with your healthcare provider. They can provide personalized advice based on your medical history and the specifics of your pregnancy. Additionally, if you experience any unusual symptoms or side effects while using the gel, you should contact your healthcare provider immediately.

In summary, Clindamycin vaginal gel is generally considered safe for use during pregnancy, particularly when prescribed for a specific condition. It is designed to be absorbed locally, minimizing the risk of systemic effects. Always consult with your healthcare provider for personalized guidance and to ensure the best outcomes for both you and your baby.

Similar Q&A

Impact of Ulecin Antibiotic on Fetal Health During Pregnancy

Hello Dr. Jan: I visited the obstetrics and gynecology department at 20 weeks of pregnancy due to vaginitis. The doctor informed me that I had an infection in the pelvic cavity and prescribed Ulecin antibiotics for me to take for a total of 14 days, but my discharge has not impro...


Dr. Li Guanghan reply Obstetrics and Gynecology
Hello: According to the Journal of Paediatrics, Obstetrics and Gynaecology, Vol. 13, in the article on drugs in pregnancy, clindamycin is considered a highly safe antibiotic during all trimesters of pregnancy, with no reports of fetal abnormalities.

[Read More] Impact of Ulecin Antibiotic on Fetal Health During Pregnancy


Medication Safety During Pregnancy: Bacitracin and Neomycin Risks

I am over 8 months pregnant. I occasionally used a topical ointment for wound care, which contains Bacitracin 500 Units and Neomycin Sulfate 5 mg (equivalent to 305 mg of Neomycin base), known as Polysporin. What effects could this have on pregnancy? Additionally, does Metronidaz...


Dr. Liao Lingmei reply Pharmacology
Dear Amy: Topical medications are generally considered safer during pregnancy than oral medications. Bacitracin is safer than Neomycin, and the safety of Neomycin is higher when the ointment base is oil-based. The main ingredient of Mentholatum is menthol, which is also considere...

[Read More] Medication Safety During Pregnancy: Bacitracin and Neomycin Risks


Choosing the Right Vaginal Suppository During Pregnancy

Currently in the second trimester of pregnancy, experiencing symptoms of cervical inflammation. In the past, the doctor prescribed "Ancozole vaginal suppositories" and "Clindamycin vaginal suppositories." Which suppository would you recommend using first? Prev...


Dr. Cao Guotao reply Obstetrics and Gynecology
Hello, using Clindamycin normally should not cause bleeding. Wishing you good health.

[Read More] Choosing the Right Vaginal Suppository During Pregnancy


Medication Safety for Pregnant Women: What You Need to Know

Hello: Can a pregnant woman take these medications? What are their effects? What are the side effects? CLEOCIN: Clindamycin is an antibiotic used to treat various bacterial infections. In pregnant women, it is generally considered safe, but it should only be used if clearly nee...


Dr. Li Guanghan reply Obstetrics and Gynecology
Hello: Please consult the physician who prescribed this medication or your obstetrician at Hsinchu Hospital, Department of Obstetrics and Gynecology.

[Read More] Medication Safety for Pregnant Women: What You Need to Know


Related FAQ

Drug Side Effects

(Obstetrics and Gynecology)

Pregnancy Medication

(Obstetrics and Gynecology)

Antibiotics

(Obstetrics and Gynecology)

Drug Interactions

(Obstetrics and Gynecology)

Folliculitis

(Obstetrics and Gynecology)

Emergency Contraceptive Pill

(Obstetrics and Gynecology)

Intrauterine Drug Delivery System

(Obstetrics and Gynecology)

Dysmenorrhea

(Obstetrics and Gynecology)

Vaginal Inflammation

(Obstetrics and Gynecology)

Menstrual Regulation Medication

(Obstetrics and Gynecology)