Can HPV Vaccine Be Administered After Thyroid Papillary Cancer? - Family Medicine

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Can a patient with stage I papillary thyroid carcinoma receive the HPV vaccine?


Hello, doctor.
I am 47 years old and underwent a total thyroidectomy for stage I papillary thyroid cancer last April.
Can I still receive the HPV vaccine? If so, does the HPV vaccine help prevent the recurrence of papillary thyroid cancer? Thank you for your assistance.

Cool Long 999, 40~49 year old female. Ask Date: 2023/02/22

Dr. Liao Yaopan reply Family Medicine


Hello, HPV (human papillomavirus) is a DNA virus that can lead to carcinogenesis.
Common related lesions include cervical intraepithelial neoplasia, cervical cancer, cancers of the external genitalia in both men and women, as well as head and neck cancers (such as oropharyngeal cancer) and anal cancer.
However, the association between this virus and thyroid cancer is not significant.
Online consultations are not equivalent to in-person medical visits and cannot provide diagnoses or treatment recommendations.
Changhua Hospital cares about you.

Reply Date: 2023/02/22

More Info


The HPV vaccine is primarily designed to prevent infections caused by the human papillomavirus (HPV), which is linked to several types of cancers, most notably cervical cancer. However, it is important to clarify that the HPV vaccine does not have any established role in the prevention or recurrence of thyroid papillary cancer or any other non-cervical cancers.
In your case, having undergone a total thyroidectomy for stage I papillary thyroid cancer, you are generally considered to be at a low risk for recurrence, especially if there are no remaining cancerous cells and you are being monitored appropriately by your healthcare team. The HPV vaccine can be administered after your thyroid cancer treatment, as there are no contraindications related to your cancer history. However, it is essential to consult with your oncologist or healthcare provider to ensure that your overall health status is stable and that there are no other underlying conditions that might affect your vaccination schedule.

Regarding the question of whether the HPV vaccine can prevent the recurrence of thyroid papillary cancer, the answer is no. The HPV vaccine is not designed to target or influence the behavior of thyroid cancer or any other cancers that are not associated with HPV. The vaccine works by stimulating the immune system to produce antibodies against specific strains of HPV, thereby reducing the risk of HPV-related cancers, such as cervical cancer, anal cancer, and oropharyngeal cancers.
For individuals who have had thyroid cancer, the focus should be on regular follow-up care, which may include blood tests for thyroid hormone levels and imaging studies to monitor for any signs of recurrence. The management of thyroid cancer is distinct from the management of HPV-related conditions, and the two should be treated separately.

In summary, you can receive the HPV vaccine after your thyroid cancer treatment, but it will not have any impact on the recurrence of your thyroid cancer. It is always best to discuss your vaccination plans with your healthcare provider, who can provide personalized advice based on your medical history and current health status. Additionally, maintaining a healthy lifestyle, including a balanced diet, regular exercise, and routine medical check-ups, can contribute positively to your overall health and well-being post-cancer treatment.

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