Can HPV Vaccine Help Prevent Recurrence of Thyroid Papillary Cancer? - Breast and Thyroid

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Can a patient with stage I papillary thyroid carcinoma receive the HPV vaccine?


Hello, doctor.
I am 47 years old and underwent a total thyroidectomy for stage I papillary thyroid cancer in April of last year.
Can I still receive the HPV vaccine? If so, does the HPV vaccine help prevent the recurrence of papillary thyroid cancer? Thank you for your assistance.

Cool Long 999, 40~49 year old female. Ask Date: 2023/02/16

Dr. Yuan Tianmin reply Breast and Thyroid


There is no evidence that the HPV vaccine can prevent the development of thyroid cancer.

Reply Date: 2023/02/16

More Info


The HPV vaccine is primarily designed to prevent infections caused by certain types of human papillomavirus (HPV), which are known to be associated with various cancers, particularly cervical cancer. However, it is important to clarify that the HPV vaccine does not have any established role in the prevention or recurrence of thyroid papillary cancer.

Thyroid papillary cancer is a type of thyroid cancer that is generally considered to have a good prognosis, especially when diagnosed at an early stage. The factors influencing the recurrence of thyroid cancer include the tumor's characteristics, such as size, presence of metastasis, and the patient's overall health. The HPV vaccine, on the other hand, targets specific HPV strains (primarily types 16 and 18) that are linked to cervical and other anogenital cancers, but there is no scientific evidence to suggest that it can influence the recurrence of thyroid cancers.

Regarding your question about receiving the HPV vaccine after undergoing total thyroidectomy for stage I papillary thyroid cancer, it is generally safe to receive the HPV vaccine post-surgery. The vaccine is recommended for individuals up to the age of 45, and since you are 47, you may want to consult with your healthcare provider about the potential benefits and any considerations specific to your health status.

If you have previously been infected with HPV, the vaccine can still provide protection against other HPV types that you may not have encountered. The immune response generated by the vaccine can help prevent future infections, but it does not treat existing infections or cancers. Therefore, if you have already been diagnosed with a type of cancer, the HPV vaccine will not affect that cancer or its recurrence.

In summary, while the HPV vaccine is an important tool in preventing certain HPV-related cancers, it does not have a role in preventing the recurrence of thyroid papillary cancer. It is advisable to discuss your specific situation with your healthcare provider, who can provide personalized recommendations based on your medical history and current health status. They can also guide you on the timing of vaccinations and any other preventive measures that may be appropriate for your overall health and cancer surveillance.

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