Oral Mucosa: White Bumps and Cancer Concerns - Dentistry

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Oral mucosa


I would like to ask the doctor about a white raised lesion on the left side of my mucosa.
It feels soft to the touch at the base, but it is rough when I touch it with my tongue.
It is not painful, and there are no ulcers.
I used to chew betel nut but have quit, although I still smoke.
I am very worried it might be oral cancer.
Thank you, doctor.

Tang Cai, 30~39 year old female. Ask Date: 2023/02/26

Dr. Lin Jiayong reply Dentistry


It is strongly recommended to visit a hospital's dental or otolaryngology department for a biopsy of the affected area.

Reply Date: 2023/02/26

More Info


When it comes to oral health, particularly concerning the presence of white bumps or lesions in the oral mucosa, it is essential to approach the situation with caution and a thorough understanding of potential underlying conditions. The symptoms you describe—soft white bumps on the left side of the oral mucosa that feel rough to the touch but are not painful—can be concerning, especially given your history of betel nut consumption and current smoking habits.
Oral mucosal lesions can arise from various causes, including benign conditions, inflammatory responses, and potentially malignant transformations. The presence of white lesions in the oral cavity is often associated with conditions such as leukoplakia, oral lichen planus, or candidiasis. Leukoplakia, in particular, is a condition characterized by white patches on the mucous membranes of the mouth that cannot be easily wiped away. While many cases of leukoplakia are benign, some can harbor dysplastic changes that may progress to oral cancer, especially in individuals with risk factors such as tobacco use.

Given your concerns about oral cancer, it is crucial to consider the following points:
1. Risk Factors: Smoking and the use of betel nut are significant risk factors for the development of oral cancer. Tobacco use is associated with an increased risk of various oral lesions, including leukoplakia and oral squamous cell carcinoma. The carcinogenic effects of these substances can lead to cellular changes in the oral mucosa, which may manifest as white lesions.

2. Duration and Changes: If the white bumps have been present for an extended period (more than two weeks) without improvement or if they change in appearance, size, or texture, it is advisable to seek further evaluation. Persistent lesions, especially those that do not heal, warrant a thorough examination by a dental or medical professional.

3. Diagnostic Evaluation: A definitive diagnosis often requires a clinical examination and possibly a biopsy of the lesion. A biopsy can help determine whether the lesion is benign or if there are any dysplastic or malignant changes present. This is particularly important if there are any concerning features, such as rough texture, induration, or changes in color.

4. Management and Follow-Up: If the lesions are determined to be benign, management may involve monitoring and lifestyle modifications, such as quitting smoking and avoiding irritants like betel nut. If dysplastic changes or malignancy are detected, appropriate treatment options will be discussed, which may include surgical excision, radiation therapy, or other modalities depending on the stage and type of cancer.

5. Oral Hygiene and Care: Maintaining good oral hygiene is essential in managing oral mucosal health. Regular dental check-ups can help monitor any changes in the oral cavity and provide early intervention if necessary.

In conclusion, while the presence of white bumps on the oral mucosa can be alarming, not all lesions are indicative of cancer. However, given your risk factors and the characteristics of the lesions, it is crucial to consult with a healthcare provider for a comprehensive evaluation. Early detection and intervention are key to managing any potential oral health issues effectively. Please do not hesitate to seek professional advice to address your concerns and ensure your oral health is monitored appropriately.

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