High Creatinine and Uric Acid Levels: What You Need to Know

Q: High Creatinine and Uric Acid Levels: What You Need to Know

Hello： In response to your inquiry, the kidney function test indicated a serum creatinine level of 1.8 mg/dL, which exceeds the normal range, suggesting impaired kidney function and the possibility of renal failure. <br>Given your age, the elevated creatinine level may indicate a

My health check-up?

Hello doctor, I found out during a health check at school that my kidney function test shows a creatinine level of 1.8 mg/dL and a uric acid level of 8 mg/dL.
What diseases could this indicate, and how should I manage it? Thank you.

Liu Xiansheng, 10~19 year old female. Ask Date: 2003/11/24

Dr. Yang Jun reply Internal Medicine

Hello: In response to your inquiry, the kidney function test indicated a serum creatinine level of 1.8 mg/dL, which exceeds the normal range, suggesting impaired kidney function and the possibility of renal failure.
Given your age, the elevated creatinine level may indicate acute kidney injury, and it is essential to seek medical attention at a nephrology clinic for further evaluation by a specialist.
Additionally, the uric acid level is at 8.0 mg/dL, which may be due to a diet high in purine-rich foods or reduced uric acid excretion resulting from impaired kidney function.
It is advisable to consult a nephrologist and a registered dietitian for dietary guidance.

Reply Date: 2003/11/24

More Info

High levels of creatinine and uric acid in your blood tests can indicate potential issues with kidney function and metabolic processes in your body. Let's break down what these results mean and how you can address them.

Understanding Creatinine Levels
Creatinine is a waste product produced from muscle metabolism and is usually filtered out of the blood by the kidneys. A normal creatinine level typically ranges from about 0.6 to 1.2 mg/dL, depending on various factors including age, sex, and muscle mass. Your level of 1.8 mg/dL is elevated, which may suggest that your kidneys are not functioning optimally.
Elevated creatinine levels can be indicative of several conditions, including:
1. Chronic Kidney Disease (CKD): This is a gradual loss of kidney function over time. It can be caused by conditions such as diabetes, hypertension, and glomerulonephritis.

2. Acute Kidney Injury (AKI): This is a sudden decrease in kidney function, which can be caused by dehydration, certain medications, or acute illnesses.

3. Obstruction: Conditions that block the urinary tract, such as kidney stones or tumors, can also lead to increased creatinine levels.

Understanding Uric Acid Levels
Uric acid is a waste product formed from the breakdown of purines, substances found in certain foods and drinks. Normal uric acid levels typically range from 2.0 to 6.0 mg/dL for women and 3.4 to 7.0 mg/dL for men. Your level of 8 mg/dL is considered high and can lead to conditions such as:
1. Gout: This is a type of arthritis characterized by sudden, severe attacks of pain, redness, and swelling in the joints, often starting with the big toe.

2. Kidney Stones: High uric acid levels can lead to the formation of stones in the kidneys, which can be painful and may require medical intervention.

3. Kidney Disease: Elevated uric acid can also be a sign of kidney dysfunction, as the kidneys are responsible for filtering uric acid from the blood.

Recommended Actions
Given your elevated creatinine and uric acid levels, here are some steps you should consider taking:
1. Consult a Healthcare Provider: It is crucial to discuss your results with a healthcare professional, preferably a nephrologist (kidney specialist). They can conduct further tests to determine the underlying cause of your elevated levels and recommend appropriate treatment.

2. Dietary Modifications:
- Reduce Purine Intake: Foods high in purines, such as red meat, organ meats, certain seafood (like sardines and anchovies), and alcohol (especially beer), can increase uric acid levels. Consider reducing or eliminating these from your diet.

- Stay Hydrated: Drinking plenty of water can help dilute uric acid in the blood and promote its excretion through urine.

- Limit Sugary Foods and Drinks: High-fructose corn syrup and sugary beverages can also contribute to increased uric acid levels.

3. Regular Monitoring: Regular follow-up blood tests to monitor your creatinine and uric acid levels will help track your kidney function and metabolic health.

4. Lifestyle Changes: Incorporating regular physical activity, maintaining a healthy weight, and managing conditions like hypertension and diabetes can significantly improve your overall health and kidney function.

5. Medication: Depending on the underlying cause of your elevated levels, your doctor may prescribe medications to help manage your condition. For example, medications like allopurinol can help lower uric acid levels.

Conclusion
Elevated creatinine and uric acid levels can be indicative of underlying health issues, particularly related to kidney function. It is essential to consult with a healthcare provider to determine the cause and appropriate treatment. By making dietary changes, staying hydrated, and following your doctor's recommendations, you can help manage your levels and maintain your overall health.

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