Alternative Treatment Options for Recurring Anal Warts in Psoriasis Patients - Urology

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Hello, doctor! I have developed genital warts around my anal area, and I am currently undergoing laser vaporization treatment to remove the lesions.
However, about two weeks after the treatment, new lesions have appeared (I plan to schedule a second laser vaporization treatment).
Since I am a psoriasis patient, I am hesitant to use oral immunosuppressive medications for treatment.
I would like to ask if there are any other treatment options you could recommend, as the recurring lesions are very distressing for me.

Qiuqiu, 40~49 year old female. Ask Date: 2023/03/07

Dr. Du Shixi reply Urology


Hello: You may also consider electrosurgical treatment.
Wishing you good health.

Reply Date: 2023/03/07

More Info


When dealing with recurring anal warts, particularly in patients with psoriasis, it is essential to consider both the underlying condition and the treatment options available. Anal warts, also known as condylomata acuminata, are caused by the human papillomavirus (HPV) and can be particularly challenging to manage, especially when they recur after treatment.

In your case, you mentioned that you have undergone laser vaporization treatment, which is a common method for removing anal warts. However, the recurrence of warts after treatment is not uncommon, and it can be frustrating. Since you are also a psoriasis patient, this complicates the situation further, as many treatments for warts may not be suitable due to their immunosuppressive effects or potential to exacerbate psoriasis.

Here are some alternative treatment options you might consider:
1. Topical Treatments: While you are cautious about using systemic immunosuppressive medications, topical treatments may be a viable option. Agents like imiquimod cream can stimulate the immune system locally and help clear the warts. However, you should discuss this with your healthcare provider to ensure it won't aggravate your psoriasis.

2. Cryotherapy: This involves freezing the warts with liquid nitrogen. Cryotherapy can be effective for some patients and may be less likely to interfere with psoriasis than systemic treatments. Multiple sessions may be needed, and it is essential to monitor the skin for any adverse reactions.

3. Electrosurgery: This technique uses electrical currents to destroy the wart tissue. It can be effective and may be an option if laser treatment is not suitable or if you prefer to avoid further laser procedures.

4. Chemical Treatments: Solutions containing trichloroacetic acid (TCA) can be applied to the warts to help destroy them. This method is often used for external warts and may be an option for you, but again, it should be discussed with your healthcare provider.

5. Immune Modulators: If you are open to it, some patients benefit from treatments that modulate the immune response, such as topical cidofovir. However, this should be approached cautiously in patients with psoriasis.

6. Lifestyle and Home Remedies: Maintaining a healthy immune system through a balanced diet, regular exercise, and stress management can also help in managing both psoriasis and HPV. Some patients find that certain dietary changes or supplements may help with their skin condition, although scientific evidence is limited.

7. Regular Follow-ups: Since you are experiencing recurrence, it is crucial to have regular follow-ups with your healthcare provider. They can monitor the situation closely and adjust your treatment plan as needed.

8. Psychological Support: Dealing with recurrent warts and psoriasis can be emotionally taxing. Consider seeking support from a mental health professional or joining a support group for individuals with similar conditions.

In conclusion, while laser vaporization is a common treatment for anal warts, the recurrence of warts can be frustrating, especially in the context of psoriasis. Exploring alternative treatments such as topical therapies, cryotherapy, or electrosurgery may provide relief. Always consult with your healthcare provider to tailor a treatment plan that considers both your anal warts and psoriasis, ensuring that any new treatment does not exacerbate your skin condition.

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