Can You Get the 9-Valent HPV Vaccine After the 2-Valent?

If someone has received the bivalent HPV vaccine, can they still receive the nine-valent HPV vaccine?

Hello, I would like to ask if it is still possible to receive the nine-valent HPV vaccine after having received the bivalent HPV vaccine 9-10 years ago during middle school.
Do you recommend getting it or is it unnecessary? Thank you.

Niming, 20~29 year old female. Ask Date: 2023/03/09

Dr. Cao Guotao reply Obstetrics and Gynecology

Hello, if you decide to get vaccinated, you will need to start the series over with three doses.
Please consider your financial situation.
Wishing you good health.

Reply Date: 2023/03/09

More Info

Yes, you can receive the 9-valent HPV vaccine after having received the 2-valent HPV vaccine. The 9-valent vaccine is designed to provide broader protection against various strains of the human papillomavirus (HPV), including those that are responsible for the majority of cervical cancers and genital warts.
The 2-valent HPV vaccine primarily protects against HPV types 16 and 18, which are known to cause about 70% of cervical cancer cases. In contrast, the 9-valent HPV vaccine covers these two types as well as an additional seven types (31, 33, 45, 52, 58, 6, and 11), which together account for approximately 90% of cervical cancer cases and the majority of genital warts.
If you received the 2-valent vaccine 9-10 years ago, it is advisable to get the 9-valent vaccine to enhance your protection against HPV. The Centers for Disease Control and Prevention (CDC) recommends that individuals who have previously received any HPV vaccine series can complete their vaccination with the 9-valent vaccine. However, it is important to note that if you choose to start the 9-valent series, you will need to complete the full series of three doses to achieve optimal immunity.

In terms of timing, there is no specific waiting period required after receiving the 2-valent vaccine before starting the 9-valent series. However, it is always best to consult with your healthcare provider to discuss your individual health history and any potential concerns you may have. They can provide personalized recommendations based on your medical history and current health status.

Regarding the necessity of receiving the 9-valent vaccine, it is generally recommended for individuals who are eligible, especially if they are within the target age range (typically up to age 26, but catch-up vaccination is recommended up to age 45 in some cases). Vaccination can significantly reduce the risk of developing HPV-related diseases, including cervical cancer and genital warts.

In summary, if you have previously received the 2-valent HPV vaccine, you can and should consider getting the 9-valent vaccine to ensure broader protection against HPV. Completing the vaccination series will provide you with the best possible defense against HPV-related health issues. Always consult with your healthcare provider for tailored advice and to address any specific concerns you may have regarding vaccination.

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