Combining Vaginal Suppositories and Oral Medications for Yeast Infections - Obstetrics and Gynecology

Share to:

Vaginal suppositories + oral medication


Hello, doctor.
Recently, I was treated for a vaginal yeast infection, and the clinic provided me with a suppository and prescribed a three-day course of oral medication (nystatin).
Since I will be starting my period in about three days, the doctor also gave me three suppositories.
Should I use the oral medication and the suppositories together for three days, or should I finish the suppositories first and then start the oral medication when my period begins? I apologize for forgetting to ask during the appointment.
Thank you for your help.

Niming, 20~29 year old female. Ask Date: 2023/03/26

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, you can use both at the same time.
If you have your period, do not use the suppository.
Wishing you good health.

Reply Date: 2023/03/26

More Info


When dealing with a yeast infection, the combination of vaginal suppositories and oral medications can be an effective treatment strategy. In your case, you have been prescribed a vaginal suppository and an oral medication (Nystatin) for three days. It’s important to understand how to properly use these medications to maximize their effectiveness.

Typically, the vaginal suppository is designed to be used for a specific duration, often for three days, as you mentioned. The oral medication, Nystatin, is also intended to be taken for a similar duration. The general recommendation is to use both treatments concurrently, meaning you would insert the vaginal suppository as directed while also taking the oral medication at the same time. This approach allows both medications to work together to combat the yeast infection more effectively.

However, if your menstrual cycle is approaching and you are concerned about the timing of your treatments, it is generally advisable to complete the full course of both the suppository and the oral medication before your period begins. If you have already started the suppository treatment, continue using it as directed for the full three days, and take the oral medication as prescribed during that same period.
If your period starts during the treatment, it’s usually fine to continue taking the oral medication. The vaginal suppository may be less effective during menstruation due to the flow, but completing the oral treatment is still important.
In summary, you should use the vaginal suppository for the full three days while also taking the oral Nystatin as directed. If you have any concerns or experience any unusual symptoms, it’s best to consult your healthcare provider for personalized advice.
Additionally, it’s important to maintain good hygiene and avoid irritants during this time. Wearing breathable cotton underwear and avoiding scented products can help reduce irritation and promote healing. If your symptoms persist after completing the treatment, or if you experience recurrent infections, further evaluation may be necessary to rule out any underlying conditions or to consider alternative treatment options.

In conclusion, combining vaginal suppositories and oral medications can be an effective treatment for yeast infections. Use both as directed, and consult your healthcare provider if you have any questions or concerns about your treatment plan.

Similar Q&A

Combining Vaginal Suppositories and Oral Medications for Yeast Infections

Hello, doctor. Recently, I was treated for a vaginal yeast infection, and the clinic provided me with a suppository and prescribed a three-day course of oral medication (nystatin). Since I will be starting my period in about three days, the doctor also gave me three suppositories...


Dr. Cao Guotao reply Obstetrics and Gynecology
Hello, oral medications and vaginal suppositories can be used together. If you have your period, do not use the suppository; wait until it is finished before using it again. Wishing you good health.

[Read More] Combining Vaginal Suppositories and Oral Medications for Yeast Infections


Is Antibiotic Treatment Effective for Vaginal Candidiasis?

Hello, I would like to ask if taking antibiotics for a vaginal Candida infection is not advisable. I have been troubled by vaginitis for a long time, and recently I mustered the courage to visit a gynecologist. The doctor diagnosed me with a Candida infection and prescribed oral ...


Dr. Hou Fangmin reply Pharmacology
Hello: A healthy vagina contains many lactobacilli, which have a bacteriostatic effect and can inhibit the growth of harmful bacteria. When immunity is lowered, hormonal changes occur, or broad-spectrum antibiotics alter the vaginal environment, it can lead to an overgrowth of Ca...

[Read More] Is Antibiotic Treatment Effective for Vaginal Candidiasis?


Can Vaginal Suppositories Cure Candida Infections Without Oral Medications?

Hello, doctor. I would like to ask if oral medications are necessary for the treatment of Candida infections. Is it possible to completely cure a Candida infection using only vaginal suppositories, or are they only effective for prevention? I have a sensitive stomach and would li...


Dr. Huang Yiwen reply Obstetrics and Gynecology
Hello Ms. Yi: For vaginal candidiasis, the first-line treatment is typically the use of vaginal suppositories. Generally, oral medications are prescribed when vaginal suppositories are ineffective or when the patient is not suitable for vaginal suppositories, such as individuals ...

[Read More] Can Vaginal Suppositories Cure Candida Infections Without Oral Medications?


Comparing Pessary and Vaginal Suppositories for Fungal Infections

Doctor, are the functions of topical antifungal creams and vaginal suppositories the same? Are both used to treat fungal infections? If one is not comfortable using suppositories, can oral medication be used as a substitute? Thank you.


Dr. Lin Wenbin reply Obstetrics and Gynecology
The efficacy of topical treatments and vaginal suppositories in treating fungal infections is similar. However, they act on different areas; suppositories can be inserted deeper into the vagina for treatment, while ointments are more suitable for infections of the vulva. If a pat...

[Read More] Comparing Pessary and Vaginal Suppositories for Fungal Infections


Related FAQ

Vaginal Suppository

(Obstetrics and Gynecology)

Candidiasis

(Obstetrics and Gynecology)

Yeast Infection

(Obstetrics and Gynecology)

Vaginitis

(Obstetrics and Gynecology)

Oral Contraceptive Pill

(Obstetrics and Gynecology)

Oral Sex

(Obstetrics and Gynecology)

Drug Interactions

(Obstetrics and Gynecology)

Vaginal Inflammation

(Obstetrics and Gynecology)

Antibiotics

(Obstetrics and Gynecology)

Trichomoniasis

(Obstetrics and Gynecology)