Safe Medication Use for Children: Key Considerations and Guidelines - Pharmacology

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Safe Medication Use in Children


Hello, Pharmacist Liao: Thank you very much for your previous assistance; it was very helpful.
I have another question.
I would like to inquire about the (Liamobol Pediatric Suppository), which seems to be a newly launched medication.

Question 1: My child had a high fever, and I previously bought a suppository (Non-Inflammatory Suppository 12.5mg).
When I went to the pharmacy the day before yesterday, they were selling the Liamobol Pediatric Suppository 125mg.
Are the usage instructions for both medications the same?
Question 2: The instruction manual for the Liamobol suppository states that it is only suitable for children under 6 years old.
My child is 11 years old; can I still use it? Will it still be effective in reducing fever?
Question 3: My child weighs 36kg.
How should I adjust the medication? Should I administer two suppositories at once, or should I use one and add a few cc of Anjare fever syrup? Currently, I have Liamobol suppositories and Anjare fever syrup for fever management.
I apologize for having to trouble a professional pharmacist again regarding medication.
Thank you, Pharmacist Liao.

Xuan Xuan, 40~49 year old female. Ask Date: 2023/03/29

Dr. Liao Lingmei reply Pharmacology


Hello:
1.
"Limaobole Children's Suppository" is classified as an "over-the-counter medication," while "Non-inflammatory Suppository" is classified as a "prescription medication." According to regulations, prescription medications require a doctor's prescription before a pharmacist can dispense them, whereas over-the-counter medications can be used as directed by a physician, pharmacist, or pharmacy technician.
Both medications are manufactured considering pediatric dosages, so their administration is similar; however, their mechanisms for antipyresis and analgesia differ, yet their effects are comparable.
Clinical observations generally indicate that the potency of the "Non-inflammatory Suppository" is greater than that of the "Limaobole Children's Suppository."
2.
The instructions for the Limaobole Suppository state that it is only suitable for children under 6 years old, but it can also be used for an 11-year-old child.
3.
Since both Limaobole Suppository and Anjia Liquid contain the same active ingredient (Acetaminophen), considering your child weighs 36 kg, you can administer 2-4 suppositories every 4-6 hours, or 15-20 c.c.
of Anjia Liquid every 4-6 hours.
These can be used interchangeably.
If you wish to combine the suppository and the oral liquid, please ensure that the total single dose does not exceed 500 mg.
Please note that the maximum daily dose of Acetaminophen should not exceed 4000 mg.
Based on the medication dosages, "Limaobole Suppository should not exceed 30 suppositories per day" and "Anjia Liquid should not exceed 160 c.c.
per day."
4.
The above dosage calculations are based on Limaobole Suppository being 125 mg per suppository and Anjia Liquid being 24 ml.

Wishing you good health.

Reply Date: 2023/03/29

More Info


When it comes to safe medication use for children, especially in the context of fever management, there are several key considerations and guidelines that parents should be aware of. Here’s a comprehensive overview based on your questions and general pediatric medication practices.


1. Understanding the Medications
Comparison of Medications: You mentioned two different medications: the non-inflammatory suppository (12.5 mg) and the newly available "理冒伯樂小兒栓劑" (125 mg). It’s essential to understand that while both may serve the purpose of reducing fever, their dosages and formulations can differ significantly. The non-inflammatory suppository is likely designed for younger children, while the new suppository may have a different concentration and intended use. Always consult a pharmacist or pediatrician to confirm that the new medication can be used in the same way as the previous one, especially regarding dosage and frequency.


2. Age and Dosage Considerations
Age Restrictions: The instruction that "理冒伯樂栓劑" is only suitable for children under 6 years old is crucial. Since your child is 11 years old, using this medication may not be advisable. Medications often have age restrictions based on safety and efficacy data, and using a product outside its recommended age range can pose risks. For an 11-year-old, it’s best to use medications specifically formulated for older children or adults, as they will have appropriate dosing and safety profiles.


3. Weight-Based Dosing
Weight Considerations: Your child weighs 36 kg, which is an important factor in determining the appropriate dosage of any medication. For fever management, it’s common to use weight-based dosing. For example, if a medication is dosed at 10-15 mg per kg, you would calculate the dose based on your child's weight.
For the "理冒伯樂栓劑," if it is indeed suitable for older children (which you should verify), you would typically not administer two suppositories at once unless specifically directed by a healthcare provider. Instead, you might consider using one suppository and then supplementing with a liquid medication like "安佳熱藥水" if needed.

4. Combination of Medications
Using Multiple Medications: When combining medications, such as a suppository and a liquid form of fever reducer, it’s essential to ensure that you are not exceeding the maximum daily dosage for either medication. For instance, if the liquid medication is also dosed based on weight, you would calculate the total amount of active ingredient your child would receive from both forms to avoid overdosing.


5. Monitoring and Safety
Observation: After administering any medication, monitor your child for any adverse reactions. Common side effects may include gastrointestinal discomfort or allergic reactions. If your child experiences any unusual symptoms, such as persistent vomiting, rash, or difficulty breathing, seek medical attention immediately.


6. Consultation with Healthcare Professionals
Professional Guidance: Given the complexities of pediatric medication, it’s always best to consult with a healthcare professional, such as a pediatrician or pharmacist, before making any changes to your child's medication regimen. They can provide personalized advice based on your child's health history and current condition.


Conclusion
In summary, when managing fever in children, it’s crucial to understand the medications being used, adhere to age and weight guidelines, and consult healthcare professionals for safe practices. Always prioritize your child's safety by verifying dosages and medication appropriateness, especially when transitioning between different formulations or brands. Your proactive approach in seeking information is commendable and essential for ensuring the well-being of your child.

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