Impact of Missed Doses on Efficacy of Etonogestrel in Gynecology - Obstetrics and Gynecology

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When it comes to the use of Etonogestrel, a progestin commonly found in contraceptive implants and some forms of hormonal birth control, missing doses can indeed impact its efficacy. Etonogestrel works primarily by inhibiting ovulation, thickening cervical mucus to prevent sperm from reaching an egg, and thinning the endometrial lining to prevent implantation.
If you have missed doses, especially if you missed two consecutive days, it can potentially reduce the effectiveness of the contraceptive method. The general guideline for progestin-only pills (also known as the "mini-pill") is that if you miss a dose by more than three hours, you should take the missed pill as soon as you remember and continue with your regular schedule. If you miss two or more pills, the recommendation is to use a backup contraceptive method, such as condoms, for at least 48 hours after resuming the pills.

In your case, since you mentioned that you missed two doses and took extra pills, this could lead to hormonal fluctuations that might affect your cycle and the overall effectiveness of the contraceptive. While taking extra pills does not necessarily counteract the missed doses, it can lead to side effects such as breakthrough bleeding or changes in your menstrual cycle.

It's also important to note that the effectiveness of Etonogestrel can be influenced by other factors, including gastrointestinal issues (like vomiting or severe diarrhea), which can affect hormone absorption. Additionally, certain medications can interact with hormonal contraceptives, potentially reducing their efficacy.

If you are concerned about the missed doses and their impact on your contraceptive effectiveness, it is advisable to consult with your healthcare provider. They can provide personalized advice based on your specific situation and may recommend additional contraceptive measures until you can ensure that the hormonal levels are back to their effective range.

In summary, missed doses of Etonogestrel can indeed affect its efficacy in preventing ovulation and, consequently, pregnancy. If you have missed doses, it is crucial to follow the guidelines for missed pills and consider using backup contraception. Always consult with your healthcare provider for tailored advice and to address any concerns regarding your contraceptive method.