Can You Take Natto and Red Orange While on Cialis 5mg? - Urology

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Can I take natto and red orange while on a maintenance dose of 5mg Cialis?


Doctor, I am currently taking 5mg of Cialis for prostate maintenance and the treatment of erectile dysfunction.
Can I take the supplement Nattokinase with it? If so, how long should I wait between taking them? Thank you for your guidance.

Bu zhi suo cuo, 40~49 year old female. Ask Date: 2023/05/19

Dr. Du Shixi reply Urology


Hello: Nattō and red orange are considered skincare products and are generally not certified as medications.
They mostly consist of various food extracts, and it is difficult to ascertain all the ingredients.
It is advisable to consult the seller.
Generally, such skincare products should not be used in excess and should not be combined with medications.
They are mostly harmless, but if you are taking multiple skincare products simultaneously, it is recommended to consult the selling unit.
Wishing you good health.

Reply Date: 2023/05/19

More Info


When considering the combination of Cialis (tadalafil) and dietary supplements like natto and red orange, it's essential to understand the potential interactions and benefits of each component involved.

Cialis is primarily used to treat erectile dysfunction and benign prostatic hyperplasia (BPH). It works by increasing blood flow to the penis, which helps achieve and maintain an erection. The active ingredient, tadalafil, is a phosphodiesterase type 5 (PDE5) inhibitor, which means it helps relax blood vessels and improve blood flow.

Natto is a traditional Japanese food made from fermented soybeans, rich in nutrients, particularly vitamin K2 and probiotics. It is known for its potential health benefits, including improving heart health and promoting bone health. Red orange, on the other hand, is a type of citrus fruit that is high in antioxidants, particularly anthocyanins, which may help reduce inflammation and improve overall cardiovascular health.

From a medical standpoint, there are no direct contraindications between taking Cialis and consuming natto or red orange. However, there are a few considerations to keep in mind:
1. Vitamin K Interaction: Natto is particularly high in vitamin K2, which plays a crucial role in blood clotting. If you are on anticoagulant medications (blood thinners), you should monitor your vitamin K intake, as it can affect the efficacy of these medications. However, if you are not on such medications, the vitamin K content in natto should not pose a problem.

2. Blood Pressure Considerations: Both natto and red orange may have beneficial effects on cardiovascular health. Natto contains compounds that can help lower blood pressure, while red orange is rich in antioxidants that can improve blood vessel function. This could potentially complement the effects of Cialis, which also works on blood flow.

3. Timing and Absorption: While there is no specific guideline on how long to wait between taking Cialis and consuming natto or red orange, it is generally advisable to space out the intake of supplements and medications by at least 1-2 hours. This allows for better absorption and minimizes any potential interactions.

4. Overall Diet and Health: Incorporating natto and red orange into your diet can be beneficial for overall health, especially for prostate health and cardiovascular function. A balanced diet rich in fruits, vegetables, whole grains, and lean proteins can support the effectiveness of medications like Cialis.

In conclusion, it is generally safe to consume natto and red orange while taking Cialis 5mg. However, it is always best to consult with your healthcare provider or a pharmacist regarding any dietary supplements, especially if you have underlying health conditions or are taking other medications. They can provide personalized advice based on your health status and medication regimen.

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