Your Pancreatic Health: AMY and Lipase Levels Explained - Family Medicine

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Health Check Report (Pancreas)


I previously had a blood test where my amylase level was 78, which is normal (the reference range on the report is [29-103]).
However, my lipase level was 117, which is elevated (the reference range is [11-82]).
Should I undergo further testing? Thank you!

tyu, 20~29 year old female. Ask Date: 2023/05/24

Dr. Ye Qianyu reply Family Medicine


Hello! It is recommended that you visit a gastroenterology and hepatology specialist.
Generally, an abdominal ultrasound examination may be arranged first, but it is important to follow the recommendations of the attending physician on-site.

Reply Date: 2023/05/24

More Info


Understanding your pancreatic health is crucial, especially when it comes to interpreting the results of tests such as Amylase (AMY) and Lipase. These enzymes are vital indicators of pancreatic function and can provide insights into various conditions affecting the pancreas.

In your case, your Amylase level is within the normal range at 78 (with a reference range of 29-103), which suggests that there is no immediate concern regarding the function of your salivary glands or pancreas in terms of Amylase production. However, your Lipase level is elevated at 117 (with a reference range of 11-82), which raises some concerns. Lipase is more specific to the pancreas than Amylase and is often used to diagnose conditions such as pancreatitis.

Elevated Lipase levels can indicate several conditions, including acute pancreatitis, chronic pancreatitis, pancreatic cancer, or even conditions unrelated to the pancreas, such as kidney disease or gastrointestinal issues. Given that your Lipase level is above the normal range, it is advisable to follow up with further testing to determine the underlying cause of this elevation.

Typically, if Lipase levels are elevated, healthcare providers may recommend additional imaging studies, such as an abdominal ultrasound or a CT scan, to visualize the pancreas and surrounding structures. These imaging studies can help identify any inflammation, cysts, or tumors that may be affecting pancreatic function. Additionally, your healthcare provider may consider other laboratory tests to assess liver function, gallbladder health, and overall metabolic status.

It is also important to consider your clinical history and any symptoms you may be experiencing. For instance, if you have had episodes of abdominal pain, nausea, or vomiting, these could be indicative of pancreatitis or other gastrointestinal issues. If you are asymptomatic, your healthcare provider may take a more conservative approach, monitoring your Lipase levels over time to see if they normalize or continue to rise.

In summary, while your Amylase levels are normal, the elevated Lipase levels warrant further investigation. It is essential to consult with a gastroenterologist or a healthcare provider specializing in pancreatic health. They can provide a comprehensive evaluation, recommend appropriate imaging studies, and interpret the results in the context of your overall health and any symptoms you may have. Early detection and management of pancreatic issues can significantly improve outcomes, so it is wise to address these findings promptly.

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