Persistent Arm Swelling and Pain After Tetanus Vaccine: What to Do? - Surgery

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Four days after receiving the tetanus vaccine, the arm is still swollen and painful?


Hello, doctor.
Last Friday, June 9th, I received a tetanus vaccine due to a deep laceration.
The injection site on my arm was sore for two days, and I expected it to improve within 2 to 3 days.
However, it has now been 4 days, and I have noticed that the bruising at the injection site has become more pronounced.
The muscles near the injection site are very stiff, and I still feel tightness in the muscles around the injection area when I raise my arm (though it’s not the same pain I felt the day after the injection).
The upper arm of my left arm where I received the injection feels completely hard.
Is there a way to relieve this through massage or other methods?
Additionally, I received an injection of 2 mg of Anxiolytic Injection and Eningyou Injection in the mental health department the Wednesday before last Friday, with all three injections administered in the upper left arm, almost in the same location.
I’m unsure if it’s possible that injecting in the same spot caused this issue, but there was a gap of about 2 days between the injections.
I’m not clear if this is a side effect or related to the injections given in the same area on Wednesday.
Is there anything that can be done to improve my current condition?

Ms. Li, 20~29 year old female. Ask Date: 2023/06/13

Dr. Chen Bingze reply Surgery


You can start with a warm compress and observe; it should gradually improve over time.

Reply Date: 2023/06/13

More Info


After receiving a tetanus vaccine, it's not uncommon to experience localized pain, swelling, or even bruising at the injection site. These symptoms are typically part of the body's immune response to the vaccine, which is designed to stimulate the immune system to produce antibodies against tetanus. However, in your case, the persistence of pain and swelling four days post-injection, along with the development of a noticeable bruise and muscle stiffness, raises some concerns that warrant further exploration.

Firstly, it's important to understand that the injection of any vaccine, including the tetanus toxoid, can lead to localized reactions. These reactions can include pain, swelling, redness, and sometimes the formation of a hard lump at the injection site. This is generally due to the inflammatory response triggered by the vaccine. In most cases, these symptoms resolve within a few days to a week. However, if symptoms persist beyond this timeframe or worsen, it may indicate a more significant issue.

In your situation, the fact that the pain and swelling have not improved after four days, and that you are experiencing increased stiffness and a hardening of the muscle in the area, suggests that you may be dealing with a more pronounced inflammatory response or possibly a localized hematoma (a collection of blood outside of blood vessels). The fact that you received additional injections in the same area just days prior could also contribute to the localized reaction, as repeated trauma to the same site can exacerbate inflammation and discomfort.

To address your concerns, here are several recommendations:
1. Rest and Ice: Initially, it is advisable to rest the affected arm and avoid any strenuous activities that could aggravate the pain. Applying ice to the injection site for 15-20 minutes several times a day can help reduce swelling and numb the pain.

2. Gentle Massage: If the area feels tight or stiff, gentle massage around the injection site may help improve circulation and alleviate some discomfort. However, be cautious not to apply too much pressure directly on the injection site if it is painful.

3. Over-the-Counter Pain Relief: Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or acetaminophen can be effective in managing pain and reducing inflammation. Be sure to follow the recommended dosages and consult with a healthcare provider if you have any contraindications.

4. Monitor Symptoms: Keep an eye on the symptoms. If the pain worsens, if you develop a fever, or if you notice any signs of infection (such as increased redness, warmth, or pus at the injection site), seek medical attention promptly.

5. Consult a Healthcare Provider: Given the persistence of your symptoms, it may be wise to consult with a healthcare provider, especially if the pain and swelling do not improve within a week. They may perform a physical examination and, if necessary, imaging studies to rule out any complications such as an abscess or other underlying issues.

In summary, while localized pain and swelling after a tetanus vaccine are common, the duration and severity of your symptoms suggest that further evaluation may be warranted. Taking steps to manage the symptoms at home while remaining vigilant for any changes is essential. If in doubt, do not hesitate to reach out to a healthcare professional for personalized advice and treatment options.

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