the Link Between Cough and Pulmonary Hypertension in Women - Cardiology

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Continuing from #197363, I would like to inquire about cough and pulmonary hypertension?


Hello, Doctor.
My background is a 37-year-old female with no history of hypertension, diabetes, or hyperlipidemia, non-smoker, non-drinker, slightly underweight, engages in minimal exercise, and does not stay up late.
I have mild gastroesophageal reflux and have experienced chest tightness for the past two weeks.
The electrocardiogram report indicates myocardial ischemia with the following diagnostic and examination purposes: 78650-1 CHEST PAIN, 78609 DYSPNEA, 413.9 OTHER AND UNSPECIFIED ANGINA PECTORIS.

M-Mode, TWO DIMENSIONAL & DOPPLER STUDIES:
- RVD: 1.3 (0.7-2.3)
- Mitral valve structure: REGURG VELOCITY STENOSIS
- LVDD: 4.4 (3.5-5.5)
- EF slope (80-370mm/s)
- Grading m/sec Gradient mmHg
- LVSD: 2.3 (1.9-3.9)
- Excursion (15-30mm)
- Max/Mean Peak/Mean
- IVS: 0.7 (0.5-1.2)
- Ao: 2.2 (1.7-4.0)
- MV: /3 / /
- LVPW: 0.7 (0.5-1.1)
- LA: 2.8 (2.0-4.0)
- AV: /3 / /
- Pericardial: □
- TV: /4 / /
- PV: /4 / /
- N ABN Description: Regional Wall Motion
- Mild hypokinesia of IVS & LV apex
- Mitral Valve: MVP, MR
- Aortic Valve: ■
- Tricuspid Valve: □ TVP TR+, RVSP=31.1 mmHg
- Pulmonary Valve: □
- Left Ventricular Function: Diastolic volume, Systolic volume, EF: 57% (50-70)
Others:
Interpretation:
1.
Normal chamber size.
2.
MVP with trivial MR.
TVP with mild TR.
3.
Mild pulmonary hypertension (RVSP: 31.1 mmHg).
4.
Normal thickness of IVS and LV walls.
5.
Mild hypokinesia of IVS and LV apex but preserved LV systolic function (LVEF= 57%).
6.
LV diastolic dysfunction (pseudonormal mitral inflow velocity pattern).
Recently, I have experienced more frequent productive coughs, triggered by throat irritation.
I currently do not have a confirmed diagnosis of COVID-19 and show no signs of a cold.
I would like to ask if this could be related to the pulmonary hypertension mentioned in the report.
What further examinations would you recommend? Thank you.

Xiao Qi, 30~39 year old female. Ask Date: 2023/06/16

Dr. He Dongjin reply Cardiology


Hello, frequent coughing with phlegm and an itchy throat that makes you want to cough are likely related to respiratory issues and are not associated with pulmonary hypertension.
Don't overthink it.
Changhua Hospital cares about you.

Reply Date: 2023/06/16

More Info


Understanding the relationship between cough and pulmonary hypertension, especially in the context of your recent health concerns, is essential. Based on your background as a 37-year-old woman with mild pulmonary hypertension (RVSP of 31.1 mmHg) and recent symptoms of cough and chest discomfort, it’s important to explore the potential connections and implications.


Cough and Pulmonary Hypertension
Coughing can be a complex symptom with various underlying causes. In the context of pulmonary hypertension (PH), it is generally not a direct symptom of the condition itself. However, pulmonary hypertension can lead to changes in the heart and lungs that may indirectly contribute to respiratory symptoms, including cough.
1. Pulmonary Hypertension Overview:
- Pulmonary hypertension is characterized by elevated blood pressure in the pulmonary arteries, which can lead to symptoms such as shortness of breath, fatigue, and chest pain. In some cases, it can also cause a cough, particularly if there is associated congestion or pressure changes in the lungs.

2. Cough Mechanisms:
- The cough you are experiencing, especially if it is productive (with phlegm), may be more related to respiratory issues rather than pulmonary hypertension itself. Conditions such as bronchitis, asthma, or even gastroesophageal reflux disease (GERD), which you mentioned having, can lead to coughing. GERD can cause irritation in the throat and lungs, leading to a reflexive cough.

3. Recent Symptoms:
- Your recent increase in coughing, particularly if it is associated with throat irritation, suggests that it may be more related to an upper respiratory issue rather than a direct consequence of pulmonary hypertension. It’s important to consider environmental factors, allergies, or infections that could be contributing to your symptoms.


Recommendations for Further Evaluation
Given your symptoms and the findings from your echocardiogram, here are some recommendations:
1. Pulmonary Function Tests:
- To assess your lung function more comprehensively, pulmonary function tests (PFTs) can help determine if there are any obstructive or restrictive patterns that may explain your cough and respiratory discomfort.

2. Chest Imaging:
- If your cough persists or worsens, a follow-up chest X-ray or CT scan may be warranted to rule out any structural lung issues, such as infections or nodules that could be contributing to your symptoms.

3. Cardiology Follow-Up:
- Since you have mild pulmonary hypertension, it would be prudent to follow up with a cardiologist to monitor your condition and assess whether any changes in your symptoms warrant further investigation or treatment.

4. GERD Management:
- Since you have a history of mild gastroesophageal reflux, managing this condition may alleviate some of your cough symptoms. Discuss with your healthcare provider about optimizing your treatment for GERD.

5. Allergy Testing:
- If you suspect that allergies may be contributing to your cough, consider discussing allergy testing with your physician.

Conclusion
While there may be a connection between your cough and pulmonary hypertension, it is more likely that your cough is due to other respiratory or gastrointestinal issues. It is essential to address these symptoms with your healthcare provider, who can guide you through the necessary evaluations and treatments. Regular monitoring of your pulmonary hypertension and addressing any respiratory symptoms will be key to managing your overall health.

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