the Complications of Epididymitis: Key Questions Answered - Urology

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The sequelae of epididymitis?


Hello, Doctor.
Recently, I have been experiencing pain and swelling in the right scrotum, which extends to the lower abdomen and lower back.
After a physical examination by a urologist, I was diagnosed with epididymitis.
A urinalysis showed elevated white blood cells (WBC > 6), and I was prescribed antibiotics (Ciprofloxacin) for seven days.
I am currently on the fifth day of the medication, but the pain persists.
Additionally, I have noticed a hard lump about 1.5 cm in size on the lower side of the right epididymis, which is also painful to touch.
Furthermore, my semen appears yellowish.
Since I plan to have children in the future, I would like to ask the doctor the following questions.
Thank you!
1.
Does the presence of a hard lump in the epididymis indicate that there will definitely be sequelae (i.e., the hardening of the affected side of the epididymis leading to blockage of the epididymis or vas deferens), resulting in an inability to transport sperm and potentially halving fertility?

2.
Following up on the previous question, how long might the hard lump take to disappear? If it does not completely resolve, will the sperm transport capability on the affected side recover?
3.
Is the yellowish appearance of the semen due to the inflammation of the epididymis?
4.
Does epididymitis always lead to the production of antisperm antibodies? If so, how should this be managed?
5.
If I still feel uncomfortable after taking the medication, should I request an ultrasound or other more aggressive examinations during my next visit?
I apologize for the many questions, and I appreciate your help.
Thank you!

A-Ren, 30~39 year old female. Ask Date: 2023/07/16

Dr. Xu Wencang reply Urology


Epididymitis is caused by a urinary tract infection, and antibiotics should be taken for 2-3 weeks.
It is important to check for the presence of Neisseria gonorrhoeae infection, which requires special antibiotics.
The lump typically resolves in 2-3 months or may leave a small remnant.
Please return for follow-up treatment.

Reply Date: 2023/07/16

More Info


Epididymitis is an inflammation of the epididymis, often caused by infections, and it can lead to various complications if not treated properly. Based on your symptoms and concerns, let’s address your questions one by one.

1. Presence of a Hard Lump in the Epididymis: The hard lump you feel in the epididymis could be due to several reasons, including inflammation, infection, or even the formation of an abscess. While it does not necessarily mean that you will have permanent damage or infertility, it is a concern that should be monitored. In some cases, if the inflammation leads to scarring or blockage of the epididymis or vas deferens, it could potentially affect sperm transport and fertility. However, many patients recover fully without long-term complications. It’s essential to follow up with your healthcare provider to monitor the situation.

2. Duration for the Hard Lump to Disappear: The time it takes for the hard lump to resolve can vary widely depending on the underlying cause. If it is due to inflammation, it may take several weeks to months for the swelling and hardness to subside after the infection is treated. If the lump does not resolve or if it persists beyond a reasonable timeframe, further evaluation may be necessary to rule out other conditions, such as a cyst or abscess. In many cases, the ability to produce sperm can return to normal if the underlying issue is resolved, but this is best assessed by your urologist.

3. Yellowish Semen: The yellowish color of your semen could indeed be related to the epididymitis. Inflammation can cause changes in the seminal fluid, including discoloration. It may also indicate the presence of pus or infection. If this symptom persists after treatment, it would be advisable to discuss it with your doctor, as it may require further investigation.

4. Antisperm Antibodies: Epididymitis can lead to the production of antisperm antibodies in some cases, particularly if there is significant inflammation or damage to the reproductive tract. These antibodies can interfere with sperm function and may affect fertility. If you are concerned about this possibility, your doctor can perform tests to check for antisperm antibodies. If present, treatment options may include medications or assisted reproductive technologies, depending on the severity of the situation.

5. Persistent Discomfort After Medication: If you are still experiencing discomfort after five days of antibiotic treatment, it is crucial to follow up with your healthcare provider. They may recommend imaging studies, such as an ultrasound, to assess the epididymis and surrounding structures for any complications, such as abscess formation or other abnormalities. Persistent symptoms may indicate that the initial treatment is not fully addressing the underlying issue, and further evaluation is warranted.

In summary, while epididymitis can lead to complications, many patients recover without long-term effects on fertility. It is essential to maintain open communication with your healthcare provider, follow their recommendations, and report any ongoing or worsening symptoms. Early intervention can help prevent potential complications and ensure the best possible outcome for your reproductive health.

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