Can You Get the Cervical Cancer Vaccine After ASCUS Pap Results? - Obstetrics and Gynecology

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Vaccine administration


Hello, I would like to ask about my Pap smear results which showed ASCUS.
I have undergone a colposcopy biopsy and am currently waiting for the pathology results.
I originally had an appointment to receive the cervical cancer vaccine.
My obstetrician-gynecologist advised me to wait for the results before getting vaccinated.
What impact could this have?

Enen, 20~29 year old female. Ask Date: 2023/07/20

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, it's better to wait for the biopsy report results before getting vaccinated.
Wishing you good health.

Reply Date: 2023/07/20

More Info


When it comes to receiving the cervical cancer vaccine (HPV vaccine) after receiving an ASCUS (Atypical Squamous Cells of Undetermined Significance) Pap smear result, it is essential to consider several factors. ASCUS is a result that indicates the presence of atypical cells on the cervix, but it does not necessarily mean that cancer is present. It is often a preliminary finding that requires further investigation, such as a colposcopy and possibly a biopsy, to determine the nature of the cells and whether any treatment is necessary.

Your gynecologist's recommendation to wait for the biopsy results before proceeding with the HPV vaccination is prudent. The rationale behind this advice is that the presence of ASCUS may indicate an underlying issue that needs to be addressed first. If the biopsy results show any significant abnormalities, such as precancerous changes or cervical cancer, the management and treatment plan may change, and it may be more critical to focus on those issues rather than vaccination at that time.

The HPV vaccine is designed to protect against certain strains of the human papillomavirus that are known to cause cervical cancer. However, if you already have an HPV infection, particularly with high-risk strains, the vaccine will not treat or eliminate the existing infection. Instead, it can help protect against other strains of HPV that you may not have been exposed to yet. Therefore, if you have already been infected with a strain covered by the vaccine, the benefit of vaccination may be limited.

In general, the HPV vaccination is recommended for individuals before they become sexually active, ideally before the age of 26, although it can be given up to age 45 in some cases. If you are within this age range and have not yet received the vaccine, it is still beneficial to get vaccinated after addressing any current health concerns, such as the results of your Pap smear and biopsy.

In summary, while it may be tempting to proceed with the HPV vaccination as scheduled, it is advisable to follow your doctor's guidance and wait for the biopsy results. This approach ensures that any potential issues are addressed appropriately and allows for a more informed decision regarding vaccination. Once you receive the results and if everything is clear, you can then proceed with the vaccination, which can provide additional protection against cervical cancer in the future.

In the meantime, it is essential to maintain regular follow-ups with your healthcare provider, adhere to any recommended screenings, and discuss any concerns you may have regarding your health and the HPV vaccine. Your health and well-being should always be the priority, and making informed decisions based on your current health status is crucial.

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