HPV, Pap Smear Results, and Cervical Cancer Vaccination

Q: HPV, Pap Smear Results, and Cervical Cancer Vaccination

Hello： The Pap smear result of 6 indicates the presence of "mild precancerous epithelial cells and koilocytic cells." The presence of koilocytic cells typically suggests a possible infection with human papillomavirus (HPV). <br>A Pap smear is merely a screening test and should no

Human Papillomavirus, Cervical Cancer Vaccine

If you have completed a Pap smear and the doctor informed you that you have tested positive for human papillomavirus (HPV), and the report states "See PAP Pats '6'," it typically refers to the classification of the Pap test results, indicating a specific level of abnormality that requires further evaluation.
The doctor also recommended that you receive the cervical cancer vaccine and suggested HPV genotyping testing.
The purpose of HPV genotyping testing is to identify the specific strain of HPV you have, which can help assess your risk for developing cervical cancer and guide further management.
Receiving the cervical cancer vaccine does not cure an existing HPV infection; however, it can protect you from other strains of HPV that you may not have been exposed to, which could potentially lead to cervical cancer in the future.
If you are advised to undergo both the HPV genotyping test and the vaccination, there is generally no strict order in which they must be done.
However, it is best to follow your healthcare provider's recommendations regarding the timing of these procedures based on your individual health needs.

Miss Zhu, 10~19 year old female. Ask Date: 2016/01/22

Dr. Yang Wangjun reply Obstetrics and Gynecology

Hello: The Pap smear result of 6 indicates the presence of "mild precancerous epithelial cells and koilocytic cells." The presence of koilocytic cells typically suggests a possible infection with human papillomavirus (HPV).
A Pap smear is merely a screening test and should not be used as a definitive diagnosis.
The next step should be a colposcopy; if the transformation zone of the squamous-columnar epithelium is fully visible and shows no lesions, then follow-up management can include HPV genotyping and a repeat Pap smear in 3 to 6 months.
If the transformation zone is not fully visible or if there are positive findings during the colposcopy, a cervical biopsy will be necessary.
Thank you for your inquiry!

Reply Date: 2016/01/22

More Info

Understanding HPV, Pap Smear Results, and Cervical Cancer Vaccination
If you have received a Pap smear result indicating that you have human papillomavirus (HPV) and the report states "See PAP Pats '6'," this typically refers to the classification of your Pap test results. The "6" likely indicates a specific category of abnormal results, often associated with the presence of dysplastic cells or precancerous changes in the cervical tissue. In this context, it suggests that there may be mild abnormalities that warrant further investigation.

Your doctor’s recommendation to receive the HPV vaccine and undergo HPV genotyping testing is significant. The HPV vaccine, such as Gardasil, is designed to protect against the most common high-risk HPV types that are associated with cervical cancer, particularly types 16 and 18. However, it is important to note that the vaccine does not treat existing HPV infections; it is preventive. Therefore, if you already have an HPV infection, the vaccine will not eliminate it. The HPV genotyping test is performed to identify the specific type of HPV you have, which can help determine the risk of developing cervical cancer and guide further management.

Regarding the sequence of vaccinations and testing, it is generally advisable to follow your healthcare provider's recommendations. If you have already been diagnosed with HPV, getting vaccinated may still be beneficial for protection against other HPV types not currently affecting you. However, the vaccination will not clear the existing infection. The timing of the HPV genotyping test and vaccination can be coordinated based on your healthcare provider's advice, but there is no strict order that must be followed.

It is also essential to understand that while the HPV vaccine significantly reduces the risk of developing cervical cancer, it does not guarantee complete immunity against all HPV types. Therefore, regular screening through Pap smears remains crucial for early detection of any cervical changes, especially if you have a history of HPV infection.

In summary, the Pap smear result indicating HPV presence requires careful follow-up. The HPV vaccine is a preventive measure and will not treat existing infections. HPV genotyping helps assess your specific risk and guide treatment decisions. Always consult with your healthcare provider for personalized advice and follow-up care. Regular screenings and vaccinations are vital components of cervical cancer prevention strategies.

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