Can HPV Virus Disappear Through Immune Strengthening? Insights for Couples - Urology

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Can the immune system strengthen and eliminate the HPV virus?


Hello, doctor.
I have a fertility plan and, based on health education concepts, I was tested positive for HPV types 59, 62, and 69.
However, I have not experienced any symptoms.
I consulted a physician who mentioned that once you have had HPV, it will always show up in tests, and there is no need to undergo painful repeated examinations.
When I asked about prevention, he replied that everything is based on probability.
After comparing some Q&A, I would like to ask if I can still have children.
I do not want to transmit the virus to my partner or future offspring.
Therefore, I would like to inquire:
1.
Is it true that the virus cannot be eliminated through immune response?
2.
According to this physician's explanation, do I not need to undergo follow-up testing? (Since it will always show up regardless of the test.)
3.
If both 1 and 2 are true, can I prevent transmission to my partner and future offspring?
4.
If I received the nine-valent vaccine but the virus strains are different, will the unassociated types still provide effective immunity?

Kevin, 30~39 year old female. Ask Date: 2023/07/28

Dr. Chen Jiansheng reply Urology


Please seek medical attention.

Reply Date: 2023/07/28

More Info


The question of whether the HPV virus can disappear through immune strengthening is a complex one, and it involves understanding the nature of HPV infections, the immune response, and the implications for couples and future offspring.

1. Can the virus be cleared by the immune system?
Yes, in many cases, the immune system can clear HPV infections. Studies suggest that approximately 70-90% of HPV infections are cleared by the immune system within two years. However, this varies by individual and by the specific type of HPV. High-risk types, such as HPV-59, 62, and 69, can persist longer and may lead to complications if not monitored. Factors such as age, overall health, and immune function can influence the body's ability to clear the virus. Therefore, while it is possible for the immune system to eliminate the virus, it is not guaranteed for everyone.

2. Do you need to continue monitoring?
Even if a healthcare provider suggests that HPV is a lifelong infection, it is essential to follow up with regular screenings. While it is true that once infected, the virus may remain dormant or undetectable, ongoing monitoring through Pap smears and HPV tests is crucial, especially for women, as persistent infections with high-risk HPV types can lead to cervical cancer. Regular check-ups can help catch any changes early, allowing for timely intervention if necessary.

3. Can you prevent transmission to your partner and offspring?
Preventing transmission to a partner involves practicing safe sex, including the use of condoms, which can reduce the risk of HPV transmission but not eliminate it entirely. Vaccination against HPV is also a critical preventive measure. The HPV vaccine is effective against several high-risk types and can help protect both partners from future infections. As for offspring, while HPV is not typically transmitted during childbirth, it is advisable to discuss any concerns with a healthcare provider. Vaccination for children, starting at ages 11-12, can provide protection before they become sexually active.

4. Does the HPV vaccine provide protection against different strains?
The HPV vaccine, particularly the nine-valent vaccine, is designed to protect against the most common high-risk HPV types, including types 16, 18, 31, 33, 45, 52, and 58, as well as low-risk types 6 and 11. If you have already been infected with certain types of HPV, the vaccine will not treat those existing infections but can still provide protection against other types that you have not yet encountered. Therefore, even if you have HPV strains that are not covered by the vaccine, getting vaccinated can still be beneficial for future protection.

In conclusion, while the immune system can clear HPV in many cases, continuous monitoring and preventive measures are essential for both personal health and the health of partners and future children. Engaging in healthy lifestyle choices, including a balanced diet, regular exercise, and stress management, can also support immune function. It is advisable to maintain open communication with healthcare providers about any concerns and to follow their recommendations for screenings and vaccinations.

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