Vaccine Reactions in Infants: A New Mom's Concerns - Pediatrics

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Vaccine issues


Hello, doctor.
I am a very anxious new mother.
On July 1st, I took my baby to receive the 13-valent and pentavalent vaccines, with one injection in each leg (both of these were the third doses).
On the first day after the vaccinations, there was redness and swelling, which resolved by the second day, but a small hard lump appeared and has not disappeared as of July 25, although it has decreased in size.
I have shown it to two pediatricians, and both said that if pressing on it does not cause the baby to cry or show pain, then it is not a concern and will naturally resolve over time.
However, the first two doses did not have this reaction.
The doctors mentioned that reactions can vary with each dose.
Is this true? How long might it take for it to go away? Thank you, doctor, as I am more nervous with my first child.

Si Si, 20~29 year old female. Ask Date: 2023/07/29

Dr. Xiao Kaiwen reply Pediatrics


The pentavalent vaccine and the 13-valent pneumonia vaccine may have a higher likelihood of side effects in subsequent doses compared to the initial doses.
This is because the immune system has already developed some memory, making reactions more pronounced later on.
Localized lumps at the injection site will gradually dissipate over time, so there is no need to worry excessively.
The duration for them to resolve can vary depending on the size of the lump.
You can apply a warm compress and gently massage the area while showering to help with absorption.

Reply Date: 2023/07/29

More Info


As a new mom, it's completely understandable to feel anxious about your baby's health, especially after vaccinations. Vaccines are crucial for protecting infants from various diseases, but they can sometimes lead to reactions that may cause concern for parents. Let's break down your situation regarding the reactions your baby experienced after receiving the 13-valent pneumococcal conjugate vaccine and the pentavalent vaccine.

Firstly, it's important to note that localized reactions at the injection site, such as redness, swelling, or hard lumps, are relatively common after vaccinations. These reactions are typically mild and resolve on their own. The fact that your baby experienced redness and swelling that subsided after a day, followed by a small hard lump, is consistent with what many parents observe. This hard lump, often referred to as a "vaccine bump," can occur due to the body's immune response to the vaccine. It is usually not a cause for concern, especially if your baby is not showing signs of pain or distress when the area is pressed.

The duration for these lumps to resolve can vary from child to child. In most cases, they can take a few days to a couple of weeks to completely disappear. Since your baby's lump has already started to decrease in size, it is a positive sign that the body is healing. Pediatricians often reassure parents that as long as the child is otherwise healthy, eating well, and not exhibiting any severe symptoms, these localized reactions are normal and will resolve with time.

It's also worth mentioning that every vaccine can elicit different reactions in different doses. Just because your baby did not have a reaction to the previous doses does not mean that a reaction will not occur with subsequent doses. Each vaccine dose can stimulate the immune system in unique ways, leading to varying responses. This variability is normal and expected.

In terms of monitoring your baby, keep an eye on the injection site for any changes. If the lump becomes increasingly painful, red, or warm, or if your baby develops a fever or other concerning symptoms, it would be wise to consult your pediatrician again. However, based on the information provided and the assessments from the pediatricians you've already consulted, it sounds like your baby's reaction is within the normal range.

As a new mom, it's natural to feel anxious about your child's health, especially when it comes to vaccinations. Remember that vaccines are an essential part of keeping your baby healthy and protected from serious diseases. If you continue to have concerns or if your baby's reaction changes, don't hesitate to reach out to your healthcare provider for further guidance. They can provide reassurance and help you navigate any worries you may have.

In conclusion, localized reactions like the one your baby is experiencing are common and typically resolve on their own. The reassurance from your pediatricians is valid, and with time, the hard lump should diminish. Trust your instincts as a parent, and always feel empowered to seek medical advice when you feel it's necessary. Your baby's health and well-being are of utmost importance, and staying informed will help you feel more confident in managing their care.

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