Impact of One Month NSAID Use on Kidney Health: What You Need to Know

Q: Impact of One Month NSAID Use on Kidney Health: What You Need to Know

Hello： Long-term use may cause kidney function damage, but it generally depends on the individual's condition. <br>For a normally healthy person, taking it for a month should not lead to any significant effects. <br>If you are very concerned, you can have a blood test to assess k

The impact of one month of NSAID use on kidney function?

Hello Doctor, I recently visited a dermatologist for a skin issue.
The doctor prescribed tetracycline and also a non-steroidal anti-inflammatory drug: enteric-coated diclofenac (two tablets a day).
I was informed that it should not be used long-term, but there was no specific guidance on when to stop the medication.
After my follow-up appointment, the prescription continued, resulting in my taking this anti-inflammatory medication for a month straight.
I have learned that this type of medication can significantly affect the kidneys, and I would like to know if my usage duration qualifies as "long-term use" and whether I need to go to the hospital for a blood test to check my kidney function.
Thank you, Doctor.

Zhang, 10~19 year old female. Ask Date: 2023/08/14

Dr. Du Shixi reply Urology

Hello: Long-term use may cause kidney function damage, but it generally depends on the individual's condition.
For a normally healthy person, taking it for a month should not lead to any significant effects.
If you are very concerned, you can have a blood test to assess kidney function.
Wishing you good health.

Reply Date: 2023/08/14

More Info

The use of non-steroidal anti-inflammatory drugs (NSAIDs) can have significant implications for kidney health, especially with prolonged use. While your one-month duration of taking NSAIDs may not be classified as "long-term" in the traditional sense, it is essential to understand the potential risks associated with their use, particularly if you have pre-existing kidney conditions or other risk factors.

NSAIDs work by inhibiting the cyclooxygenase (COX) enzymes, which play a crucial role in the production of prostaglandins. Prostaglandins are compounds that help maintain blood flow to the kidneys and regulate kidney function. When NSAIDs are taken, especially over an extended period, they can reduce the production of these protective prostaglandins, leading to decreased renal blood flow and potentially causing acute kidney injury (AKI) or exacerbating chronic kidney disease (CKD).

In your case, taking NSAIDs for a month may not seem excessive, but it is crucial to consider individual factors such as your overall health, existing medical conditions, and any other medications you may be taking. If you have a history of kidney issues, hypertension, diabetes, or if you are taking other medications that may affect kidney function, the risk of kidney damage increases.
Regarding the need for kidney function tests, it is generally advisable to monitor kidney health if you have been using NSAIDs for an extended period, especially if you experience any symptoms such as changes in urination, swelling, fatigue, or unexplained weight gain. Blood tests, including serum creatinine and blood urea nitrogen (BUN), can provide valuable insights into your kidney function. Additionally, a urinalysis may help identify any abnormalities in your urine that could indicate kidney distress.

If you are concerned about the impact of NSAIDs on your kidneys, it is prudent to consult your healthcare provider. They can assess your individual risk factors, review your medication regimen, and determine whether kidney function tests are necessary. It is also essential to communicate openly with your healthcare provider about any side effects or symptoms you may be experiencing while taking these medications.

In summary, while one month of NSAID use may not typically be classified as long-term, it is essential to be vigilant about potential kidney health implications. Regular monitoring and open communication with your healthcare provider can help ensure that any risks are managed appropriately. If you have any concerns or experience any symptoms, do not hesitate to seek medical advice. Your health and well-being should always be the top priority.

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Impact of One Month NSAID Use on Kidney Health: What You Need to Know

Hello Doctor, I recently visited a dermatologist due to skin issues. The doctor prescribed tetracycline and also a non-steroidal anti-inflammatory drug: enteric-coated diclofenac (two tablets a day). I was informed that it should not be used long-term, but there was no specific g...

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