the Effects of Ethinyl Estradiol on Menstrual Irregularities - Obstetrics and Gynecology

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Hello Doctor, in my previous question, I mentioned that I have polycystic ovary syndrome, which is causing my irregular menstrual cycle.
When I visited the gynecologist, the doctor prescribed me "Jing Tian Na Neng Ning" (Ethinyl Estradiol) tablets.
I would like to ask if this medication is intended to induce menstruation or delay it? (Because I am currently on the fourth day of taking it, and the discharge is the same as when I don't have my period, which is just clear.) Is it possible that I might get my period about a week after starting the medication? Thank you for your response!

Hui, 20~29 year old female. Ask Date: 2023/08/15

Dr. Lin Xinwang reply Obstetrics and Gynecology


Hello Hui: During the medication period, menstruation will not occur.
After finishing the medication and stopping it, menstruation will typically come within 2 to 7 days.

Reply Date: 2023/08/15

More Info


Ethinyl estradiol is a synthetic form of estrogen, commonly used in various hormonal therapies, including contraceptives and treatments for menstrual irregularities. In the context of polycystic ovary syndrome (PCOS), which you mentioned, ethinyl estradiol can play a significant role in regulating menstrual cycles and addressing symptoms associated with hormonal imbalances.


Mechanism of Action
Ethinyl estradiol works primarily by mimicking the natural hormone estrogen in the body. It helps to regulate the menstrual cycle by promoting the growth of the uterine lining (endometrium) and ensuring that it is shed appropriately during menstruation. In women with PCOS, where hormonal imbalances can lead to irregular or absent menstrual periods, ethinyl estradiol can help restore a more regular cycle.


Effects on Menstrual Irregularities
1. Inducing Menstruation: Ethinyl estradiol can help induce menstruation in women who have irregular cycles. By providing a consistent source of estrogen, it can stimulate the endometrium to grow and eventually shed, leading to a menstrual period. This is particularly beneficial for women with PCOS, who may experience anovulation (lack of ovulation) and, consequently, irregular periods.

2. Regulating Cycles: In addition to inducing menstruation, ethinyl estradiol can help regulate the menstrual cycle over time. Regular use can lead to more predictable cycles, which can be beneficial for women managing PCOS symptoms.

3. Reducing Symptoms: Ethinyl estradiol can also help alleviate other symptoms associated with PCOS, such as excessive hair growth (hirsutism) and acne, by balancing hormone levels in the body.


Expected Outcomes
Regarding your specific question about whether ethinyl estradiol acts to "催經" (induce menstruation) or "延經" (delay menstruation), it is primarily used to induce menstruation in cases of irregular cycles. If you are on the fourth day of treatment and noticing clear discharge similar to what you experience when not menstruating, it may take some time for the medication to take effect. Typically, if the medication is effective, you might expect to see a menstrual period within a week or so after starting the treatment, but this can vary based on individual responses to the medication.


Considerations and Monitoring
- Timing: It’s important to give the medication some time to work. If you do not experience a menstrual period within a week or if you have concerns about your symptoms, it is advisable to follow up with your healthcare provider for further evaluation.


- Side Effects: While ethinyl estradiol is generally well-tolerated, some women may experience side effects such as nausea, breast tenderness, or mood changes. If you notice any severe or concerning symptoms, you should contact your healthcare provider.

- Long-term Use: If you are considering long-term use of ethinyl estradiol, it is essential to discuss this with your doctor, as they can monitor for potential risks, including blood clots and other hormonal side effects.

In conclusion, ethinyl estradiol is typically used to induce menstruation and regulate cycles in women with conditions like PCOS. If you have further questions or concerns about your treatment, it is always best to consult with your healthcare provider for personalized advice and management.

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