Shingles: Symptoms, Triggers, and Arginine Intake

Shingles

Previously, I was physically exhausted and underwent a blood test, which revealed that I had shingles.
Later, I learned that I had chickenpox as a child; however, I have never experienced symptoms related to shingles, such as a rash.
I do occasionally have brief episodes of cramping pain on my side or right chest.

1.
I would like to know if the brief cramping pain is related to shingles?
2.
I have been working out and taking dietary supplements.
I heard that taking arginine can reactivate shingles; is this true?
3.
If this is true, what is the maximum daily dosage of arginine that should not be exceeded?

chen, 30~39 year old female. Ask Date: 2023/08/16

Dr. Ye Qianyu reply Family Medicine

Hello! A blood test can only confirm if you have had chickenpox.
Chickenpox and shingles are diseases caused by the same virus; the initial infection is called chickenpox, and after that, the virus remains dormant in the body.
When the immune system is compromised, it can reactivate in the local nerve ganglia, resulting in shingles.
To answer your questions in order: 1.
Shingles typically presents with skin blisters; if you are experiencing only brief muscle cramps, it may simply be due to muscle fatigue.
2.
Currently, there is no evidence linking arginine to shingles.
3.
Evidence suggests that lysine may have a preventive effect against herpes simplex virus.
Since arginine and lysine share the same transport protein, using them together may create an antagonistic effect and reduce their absorption rates.
The recommended daily intake of L-arginine for adults is 117 mg per kilogram of body weight, with a single dose not exceeding 9 grams, which can also be obtained from natural dietary sources.

Reply Date: 2023/08/16

More Info

Shingles, also known as herpes zoster, is a viral infection caused by the varicella-zoster virus (VZV), which is the same virus that causes chickenpox. After a person recovers from chickenpox, the virus remains dormant in the nerve tissues and can reactivate later in life, leading to shingles. Understanding the symptoms, triggers, and dietary considerations, such as arginine intake, is crucial for managing this condition.

1. Short-term Cramping Pain and Shingles: The short-term cramping pain you describe in your side or right chest could potentially be related to shingles, especially if it occurs in a dermatomal pattern (following the path of a nerve). However, it's important to note that not everyone with shingles will exhibit the classic rash or "snake-like" appearance of blisters. Some individuals may experience pain or discomfort without the visible rash, a condition known as "zoster sine herpete." This pain can manifest as sharp, burning, or cramping sensations, often described as neuropathic pain. If you suspect that your symptoms may be related to shingles, it is advisable to consult a healthcare professional for a thorough evaluation and appropriate management.

2. Arginine and Shingles Activation: Arginine is an amino acid that plays a role in various physiological processes, including protein synthesis and immune function. However, there is some evidence suggesting that arginine may promote the replication of certain viruses, including the herpes simplex virus (HSV). While the relationship between arginine and the varicella-zoster virus (the cause of shingles) is less clear, some healthcare providers recommend caution with arginine supplementation in individuals with a history of herpes infections. This is because high levels of arginine could theoretically create an environment conducive to viral reactivation. If you are concerned about the potential effects of arginine on shingles, it would be prudent to discuss this with your healthcare provider.

3. Recommended Daily Intake of Arginine: There is no established upper limit for arginine intake, as it is generally considered safe when consumed in typical dietary amounts. However, if you are considering supplementation, it is often recommended to limit doses to around 3 to 6 grams per day, depending on individual health needs and conditions. It's essential to consult with a healthcare professional before starting any new supplement, especially if you have a history of viral infections or other health concerns.

In summary, while your short-term cramping pain could be related to shingles, it is essential to seek medical advice for a definitive diagnosis. Regarding arginine, moderation is key, and discussing your dietary supplements with a healthcare provider can help ensure they align with your health goals and conditions. Always prioritize open communication with your healthcare team to manage your health effectively.

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