Muscle Twitches and Weakness After Illness: A Neurological Perspective - Neurology

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Muscle twitching accompanied by mild weakness?


Hello Doctor, I am 21 years old.
About a week ago, I had a cold, and in the past few days, I have started to experience mild weakness in my right leg, especially noticeable when sitting.
This is accompanied by occasional muscle twitching near the knee.
I have been worried, so I tried some leg exercises like jumping rope, quick steps in place, and squat jumps, which I was able to complete without difficulty.
I do not have issues like difficulty using chopsticks or swallowing.
However, I feel very anxious about the leg weakness and muscle twitching, fearing it might be amyotrophic lateral sclerosis (ALS).
I would like to know your opinion, thank you.
————————————————————————
Later, I visited an orthopedic doctor who said that the weakness in my legs and the muscle twitching around my knees were due to inflammation in both of my knees.
After treatment and rehabilitation, the weakness has indeed decreased, but it still persists.
However, the muscle twitching has now occurred in both legs, and my triceps occasionally twitch as well, though not as frequently.
I am wondering if this could be due to the significant stress from preparing for my exams, which has made me very anxious, and the fact that I have been sitting for long periods without much exercise over the past two months.
Recently, I have started to resume some exercise, such as lifting dumbbells and doing squats and jumping jacks, which I can complete successfully.
However, after using my legs for a while, the weakness starts to return, and I occasionally feel an electric shock sensation around my knees.
This has made me anxious again, and I would like to ask the doctor what is going on.
(I had a cold about two to three weeks ago.)

Mian, 20~29 year old female. Ask Date: 2023/09/08

Dr. Peng Shiwei reply Neurology


Hello, it is rare for individuals with amyotrophic lateral sclerosis (ALS) to occur at your age.
Additionally, the exercises you have been practicing recently require frequent use of the knees.
I recommend consulting with a sports medicine specialist or an orthopedic physician to discuss more suitable exercise options.
Thank you for your inquiry.

Reply Date: 2023/09/08

More Info


It sounds like you are experiencing a combination of muscle weakness and twitching in your legs, which has understandably caused you a lot of anxiety, especially given your concerns about serious conditions like Amyotrophic Lateral Sclerosis (ALS). Let's break down your symptoms and the potential causes, as well as the appropriate steps you can take moving forward.

Firstly, it's important to note that muscle twitching (also known as fasciculations) and feelings of weakness can occur for a variety of reasons, many of which are benign. In your case, the onset of these symptoms following a recent illness (like a cold) could suggest a few possibilities. Viral infections can sometimes lead to temporary muscle weakness or twitching due to inflammation or irritation of the nerves and muscles. This is often referred to as post-viral fatigue or post-viral syndrome, where the body takes time to recover fully after an illness.

You mentioned that you have been feeling particularly anxious about your symptoms and that you have been under significant stress due to exam preparations. Stress and anxiety can exacerbate physical symptoms, leading to increased muscle tension and twitching. Additionally, prolonged periods of inactivity, such as sitting for long hours while studying, can lead to muscle deconditioning, which might explain the feelings of weakness you are experiencing.

The fact that you are able to perform exercises like jumping rope and squats without significant difficulty is a positive sign. It suggests that your muscle strength is not severely compromised. However, the persistence of weakness and twitching, particularly after exertion, indicates that your muscles may still be recovering from the recent illness or from the effects of stress and inactivity.

You mentioned that a doctor diagnosed you with knee inflammation, which can also contribute to feelings of weakness and discomfort in the legs. Inflammation can affect how your muscles function, leading to a sensation of weakness or instability. Treatment for inflammation, including physical therapy and appropriate exercises, can help alleviate these symptoms over time.

To address your concerns about ALS, it's important to understand that this condition typically presents with progressive weakness and muscle atrophy, not just temporary symptoms following an illness. ALS symptoms usually worsen over time, and the muscle weakness is often accompanied by other signs, such as difficulty speaking or swallowing, which you have not reported. Additionally, ALS is relatively rare, especially in younger individuals like yourself.

Here are some recommendations for managing your symptoms:
1. Stay Active: Continue with light to moderate exercise as tolerated. Activities like walking, stretching, and strength training can help maintain muscle function and reduce feelings of weakness.

2. Manage Stress: Incorporate stress-reducing techniques into your routine, such as mindfulness, meditation, or yoga. These practices can help alleviate anxiety and may reduce muscle tension.

3. Monitor Symptoms: Keep track of your symptoms and any changes you notice. If your weakness or twitching worsens or if you develop new symptoms, it would be wise to consult a healthcare professional for further evaluation.

4. Seek Professional Guidance: If your symptoms persist or if you have ongoing concerns, consider seeing a neurologist. They can perform a thorough examination and may recommend tests, such as an electromyography (EMG) or nerve conduction studies, to assess your muscle and nerve function.

5. Nutrition and Hydration: Ensure you are eating a balanced diet and staying hydrated, as proper nutrition can support muscle health and recovery.

In conclusion, while your symptoms are understandably concerning, they are likely related to the recent illness, stress, and possibly inflammation rather than a serious neurological condition. By staying active, managing stress, and seeking appropriate medical advice, you can work towards alleviating your symptoms and improving your overall well-being.

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