Allergies and Joint Pain: Insights on Rheumatoid Arthritis - Internal Medicine

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Inquiry about Rheumatoid Arthritis


Hello, Doctor.
Over the past two to three years, I have frequently experienced skin allergies (rashes).
When I am back in my hometown (Miaoli), my condition improves significantly during my vacation, but it immediately relapses when I return to my workplace (Guishan).
I have an anxious constitution and have recently experienced gastrointestinal discomfort and inflammation.
I usually sleep about six hours a night (occasionally experiencing insomnia).

Recently, I have been experiencing the following symptoms:
- Allergic reaction in my eyes with conjunctival edema, which improved after applying ice.

- Slight discomfort in my wrist joints, pain in both shoulders, neck, and shoulder joints, upper back pain, and mild discomfort in my knees.

- Pain in my elbows at specific angles (initially in both elbows, but now only in one).

On July 12, I had blood tests that showed E.C.P.
at 28.8, Total IgE at 68.3, and PHADIATOP at 1.84.

I would like to ask the doctor:
1.
Given my long-term recurring allergies, could they be caused by environmental factors, stress, or irregular lifestyle? What should I pay attention to or how can I improve my situation?
2.
Could the symptoms mentioned above be indicative of rheumatoid arthritis? Or would I need more detailed blood tests to assist in the diagnosis? I am a bit worried as someone close to me recently passed away from this disease.

Thank you for your assistance.

ab, 30~39 year old female. Ask Date: 2023/09/11

Dr. Gao Jiankai reply Internal Medicine


Hello, thank you for your question.
Here are my responses:
1.
For someone like me who experiences long-term allergies that recur, could it be due to environmental factors, stress, or irregular lifestyle? What should I pay attention to or how can I improve? --> All three factors are possible.
I recommend starting with regular exercise; even walking can be beneficial.
Find an activity that you can maintain consistently, as it can help reduce stress and anxiety while soothing the immune system, thereby decreasing the chances of allergic reactions—it's a win-win situation.
2.
Could the symptoms mentioned above be related to rheumatoid arthritis, or is it necessary to conduct blood tests for more detailed data to assist in the diagnosis? --> The symptoms mentioned are related to allergic reactions.
If you are concerned about rheumatoid arthritis, further examinations should be arranged, and a physician should evaluate the condition of your joints for a more accurate assessment.
However, since your joint symptoms have been present for a short time, you might choose to observe for a few more days, as sometimes acute joint symptoms can resolve on their own.

Best regards from the Allergy, Immunology, and Rheumatology Department of Changhua Hospital, Ministry of Health and Welfare.

Reply Date: 2023/09/11

More Info


Thank you for your inquiry regarding the relationship between allergies, joint pain, and the potential for rheumatoid arthritis (RA). Your symptoms and concerns are quite valid, and it's important to address them comprehensively.

1. Understanding Allergies and Their Triggers: Your experience of skin allergies that improve in one location (Miaoli) but worsen in another (Guishan) suggests a possible environmental trigger. Allergies can be influenced by various factors, including pollen, dust mites, mold, and even stress. Stress can exacerbate allergic reactions and may also contribute to inflammation in the body. It’s crucial to identify specific allergens through testing and to consider lifestyle changes that may reduce exposure to these triggers. For instance, maintaining a clean living environment, using air purifiers, and managing stress through relaxation techniques can be beneficial.

2. Joint Pain and Its Possible Causes: The joint discomfort you describe, including wrist pain, shoulder and neck discomfort, and knee issues, could be related to several factors. While rheumatoid arthritis is a possibility, it is characterized by symmetrical joint involvement, morning stiffness, and systemic symptoms such as fatigue and fever. Your symptoms, particularly the episodic nature of the pain and the specific joint involvement, may suggest a different underlying issue, such as reactive arthritis or even a form of tendinitis, especially if they are linked to repetitive activities or strain.

3. Rheumatoid Arthritis Considerations: To determine if your symptoms are indicative of rheumatoid arthritis, further blood tests can be helpful. Common tests include rheumatoid factor (RF), anti-citrullinated protein antibodies (anti-CCP), and inflammatory markers such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). Given your elevated total IgE and ECP levels, it’s also worth considering whether an allergic reaction could be contributing to your symptoms. Allergies can lead to systemic inflammation, which may exacerbate joint pain.

4. Next Steps for Diagnosis and Management: Given your concerns, it would be prudent to consult a rheumatologist who can conduct a thorough evaluation, including a physical examination and appropriate laboratory tests. They can help rule out or confirm rheumatoid arthritis and other autoimmune conditions. If RA is ruled out, they may explore other causes of your joint pain, such as inflammatory arthritis or even mechanical issues related to posture or repetitive strain.

5. Lifestyle Modifications and Treatment: In the meantime, consider implementing lifestyle changes that may alleviate your symptoms. Regular low-impact exercise, such as swimming or cycling, can improve joint mobility and reduce stiffness. Additionally, maintaining a balanced diet rich in anti-inflammatory foods (like omega-3 fatty acids found in fish, nuts, and seeds) may help manage inflammation. Adequate sleep and stress management techniques, such as mindfulness or yoga, can also play a crucial role in overall health.

In summary, while your symptoms may raise concerns about rheumatoid arthritis, they could also be attributed to other factors, including allergies and environmental triggers. A comprehensive evaluation by a healthcare professional specializing in rheumatology will provide clarity and guide you toward the appropriate management strategies. Don’t hesitate to seek help, as early intervention can significantly improve outcomes in managing both allergies and joint pain.

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